简单幻听中意识的事件相关电位相关性 ☆.

IF 4.7 2区医学 Q1 NEUROIMAGING

NeuroImage Pub Date : 2025-03-22 DOI:10.1016/j.neuroimage.2025.121168

Dmitri Filimonov , Saana Lenkkeri , Mika Koivisto , Antti Revonsuo

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引用次数: 0

摘要

针对各种感官模式的知觉意识，人们提出了意识的神经相关性（NCC）。迄今为止，知觉意识负性（PAN）和晚期正性（LP）被认为是主要的 NCC 候选者，问题仍然是哪一个才是 NCC 本体。研究意识内容独立于物理刺激的状态，可能会提供更多的理论和实证价值。我们使用巴甫洛夫条件反射范式研究了简单听觉幻觉中听觉意识的事件相关电位（ERP）标记，让参与者聆听近阈值音调和刺激缺失试验，并用知觉意识量表（PAS）评定主观清晰度。结果显示，幻觉状态下的听觉意识负性（AAN）--意识到和未意识到的刺激之间的早期事件相关电位差--表明AAN是听觉意识的NCC本征。在简单的幻听中则不存在晚期阳性。

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Event-related potential correlates of consciousness in simple auditory hallucinations

Neural correlates of consciousness (NCC) have been proposed for perceptual awareness in various sensory modalities. To date, perceptual awareness negativity (PAN) and late positivity (LP) are considered the main NCC candidates, and the question remains which one is the NCC proper. Investigating states where the content of consciousness is independent of the physical stimulus, may provide additional theoretical and empirical value. We studied the event-related potential (ERP) markers of auditory awareness in simple auditory hallucinations using a Pavlovian conditioning paradigm, where participants listened to the near-threshold tones and stimulus-absent trials, rating subjective clarity with the perceptual awareness scale (PAS). The results showed auditory awareness negativity (AAN) — an early event-related potential difference between aware and unaware stimuli — in the hallucinatory condition, suggesting that AAN is an NCC proper in auditory consciousness. Late positivity was absent in simple auditory hallucinations.

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来源期刊

NeuroImage 医学-核医学

CiteScore

11.30

自引率

10.50%

发文量

809

审稿时长

63 days

期刊介绍： NeuroImage, a Journal of Brain Function provides a vehicle for communicating important advances in acquiring, analyzing, and modelling neuroimaging data and in applying these techniques to the study of structure-function and brain-behavior relationships. Though the emphasis is on the macroscopic level of human brain organization, meso-and microscopic neuroimaging across all species will be considered if informative for understanding the aforementioned relationships.