Shahzad Akbar, Usama Shahzore, Tanzila Saba, Faten S Alamri, Sadaf S Khan, Amjad R Khan
{"title":"使用深度学习模型的显微镜辅助高血压视网膜病变诊断。","authors":"Shahzad Akbar, Usama Shahzore, Tanzila Saba, Faten S Alamri, Sadaf S Khan, Amjad R Khan","doi":"10.1002/jemt.24847","DOIUrl":null,"url":null,"abstract":"<p><p>The retina is the most crucial part of the human eye, and it can be affected due to hypertension. However, retinal abnormalities due to hypertension are termed hypertensive retinopathy (HR). A severe stage of HR can lead to complete blindness if not diagnosed and treated on time. Manually analyzing retinal images for HR diagnosis is time-consuming and prone to errors. This research article provides a novel technique based on U-Net and Dense-Net for automatic HR detection and grading through retinal images. The presented method consists of preprocessing, vessel segmentation, artery or vein (A/V) classification, and vessel width calculation to compute the arteriovenous ratio (AVR). In the preprocessing phase, the Gabor filter is applied to the retinal image to enhance the vascular network of the image. The preprocessed image is fed into the U-Net architecture to segment the vascular network image. The segmented vascular network image is fed into the Dense-Net architecture for A/V classification. The A/V classified vascular network is divided into several artery and vein segments at the bifurcation and crossover points. The A/V segments are labeled for width calculation to compute the AVR. The AVR is a standard parameter for HR detection and grading. The evaluation results show an average accuracy of 99.40% in HR classification and 99.77% in HR grading on the AVRDB dataset. The evaluated results are beneficial for the automatic HR detection and grading for clinical purposes.</p>","PeriodicalId":18684,"journal":{"name":"Microscopy Research and Technique","volume":" ","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Microscope-Assisted Hypertensive Retinopathy Diagnosis Using Deep Learning Models.\",\"authors\":\"Shahzad Akbar, Usama Shahzore, Tanzila Saba, Faten S Alamri, Sadaf S Khan, Amjad R Khan\",\"doi\":\"10.1002/jemt.24847\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The retina is the most crucial part of the human eye, and it can be affected due to hypertension. However, retinal abnormalities due to hypertension are termed hypertensive retinopathy (HR). A severe stage of HR can lead to complete blindness if not diagnosed and treated on time. Manually analyzing retinal images for HR diagnosis is time-consuming and prone to errors. This research article provides a novel technique based on U-Net and Dense-Net for automatic HR detection and grading through retinal images. The presented method consists of preprocessing, vessel segmentation, artery or vein (A/V) classification, and vessel width calculation to compute the arteriovenous ratio (AVR). In the preprocessing phase, the Gabor filter is applied to the retinal image to enhance the vascular network of the image. The preprocessed image is fed into the U-Net architecture to segment the vascular network image. The segmented vascular network image is fed into the Dense-Net architecture for A/V classification. The A/V classified vascular network is divided into several artery and vein segments at the bifurcation and crossover points. The A/V segments are labeled for width calculation to compute the AVR. The AVR is a standard parameter for HR detection and grading. The evaluation results show an average accuracy of 99.40% in HR classification and 99.77% in HR grading on the AVRDB dataset. The evaluated results are beneficial for the automatic HR detection and grading for clinical purposes.</p>\",\"PeriodicalId\":18684,\"journal\":{\"name\":\"Microscopy Research and Technique\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2025-03-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Microscopy Research and Technique\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1002/jemt.24847\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ANATOMY & MORPHOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microscopy Research and Technique","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1002/jemt.24847","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ANATOMY & MORPHOLOGY","Score":null,"Total":0}
Microscope-Assisted Hypertensive Retinopathy Diagnosis Using Deep Learning Models.
The retina is the most crucial part of the human eye, and it can be affected due to hypertension. However, retinal abnormalities due to hypertension are termed hypertensive retinopathy (HR). A severe stage of HR can lead to complete blindness if not diagnosed and treated on time. Manually analyzing retinal images for HR diagnosis is time-consuming and prone to errors. This research article provides a novel technique based on U-Net and Dense-Net for automatic HR detection and grading through retinal images. The presented method consists of preprocessing, vessel segmentation, artery or vein (A/V) classification, and vessel width calculation to compute the arteriovenous ratio (AVR). In the preprocessing phase, the Gabor filter is applied to the retinal image to enhance the vascular network of the image. The preprocessed image is fed into the U-Net architecture to segment the vascular network image. The segmented vascular network image is fed into the Dense-Net architecture for A/V classification. The A/V classified vascular network is divided into several artery and vein segments at the bifurcation and crossover points. The A/V segments are labeled for width calculation to compute the AVR. The AVR is a standard parameter for HR detection and grading. The evaluation results show an average accuracy of 99.40% in HR classification and 99.77% in HR grading on the AVRDB dataset. The evaluated results are beneficial for the automatic HR detection and grading for clinical purposes.
期刊介绍:
Microscopy Research and Technique (MRT) publishes articles on all aspects of advanced microscopy original architecture and methodologies with applications in the biological, clinical, chemical, and materials sciences. Original basic and applied research as well as technical papers dealing with the various subsets of microscopy are encouraged. MRT is the right form for those developing new microscopy methods or using the microscope to answer key questions in basic and applied research.