So Young Kim, Hyo Geun Choi, Joo-Hee Kim, Dae Myoung Yoo, Kyeongmin Han, Na-Eun Lee, Mi Jung Kwon, Ho Suk Kang
{"title":"突发性感觉神经性听力损失与既往慢性牙周炎发病率的关系。","authors":"So Young Kim, Hyo Geun Choi, Joo-Hee Kim, Dae Myoung Yoo, Kyeongmin Han, Na-Eun Lee, Mi Jung Kwon, Ho Suk Kang","doi":"10.21053/ceo.2024.00297","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Chronic periodontitis (CP) has been linked to an increased risk of sudden sensorineural hearing loss (SSNHL). This study aimed to delineate the causal relationships between CP and SSNHL.</p><p><strong>Methods: </strong>Data from participants aged 40 years or older in the Korean National Health Insurance Service-Health Screening Cohort from 2002 through 2019 were used. Data for 13,769 patients with SSNHL were collected and matched with those for 55,076 control participants based on demographic and socioeconomic variables. The incidence of CP before the onset of SSNHL was recorded. The odds ratios (ORs) for SSNHL based on CP history were calculated using conditional logistic regression. ORs were analyzed according to the frequency of CP, specifically ≥1, ≥2, and ≥3 clinic visits for CP within 1 year and ≥1 visit within 2 years. Sensitivity analyses were also conducted for all covariables.</p><p><strong>Results: </strong>The patients with SSNHL had a higher mean number of CP visits (0.71 within 1 year and 1.34 within 2 years) compared with control participants. CP was associated with increased odds of SSNHL, with an OR of 1.14 (95% CI, 1.10-1.19) for ≥1 CP visit, an OR of 1.09 (95% CI, 1.03-1.15) for ≥2 visits, and an OR of 1.09 (95% CI, 1.02-1.17) for ≥3 visits within 1 year. Furthermore, having experienced at least 1 visit for CP within 2 years was associated with 1.15 times greater odds of SSNHL (95% CI, 1.10-1.19). Higher rates of SSNHL were also observed in the subgroups of participants with underweight, overweight, and age ≥65 years, as well as those with comorbidities.</p><p><strong>Conclusion: </strong>CP was linked to an elevated incidence of SSNHL. Individuals with comorbidities, advanced age, or abnormal body weight were more likely to exhibit both CP and SSNHL.</p>","PeriodicalId":10318,"journal":{"name":"Clinical and Experimental Otorhinolaryngology","volume":" ","pages":"225-233"},"PeriodicalIF":3.4000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12400140/pdf/","citationCount":"0","resultStr":"{\"title\":\"Relationship of Sudden Sensorineural Hearing Loss With History of Chronic Periodontitis.\",\"authors\":\"So Young Kim, Hyo Geun Choi, Joo-Hee Kim, Dae Myoung Yoo, Kyeongmin Han, Na-Eun Lee, Mi Jung Kwon, Ho Suk Kang\",\"doi\":\"10.21053/ceo.2024.00297\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>Chronic periodontitis (CP) has been linked to an increased risk of sudden sensorineural hearing loss (SSNHL). This study aimed to delineate the causal relationships between CP and SSNHL.</p><p><strong>Methods: </strong>Data from participants aged 40 years or older in the Korean National Health Insurance Service-Health Screening Cohort from 2002 through 2019 were used. Data for 13,769 patients with SSNHL were collected and matched with those for 55,076 control participants based on demographic and socioeconomic variables. The incidence of CP before the onset of SSNHL was recorded. The odds ratios (ORs) for SSNHL based on CP history were calculated using conditional logistic regression. ORs were analyzed according to the frequency of CP, specifically ≥1, ≥2, and ≥3 clinic visits for CP within 1 year and ≥1 visit within 2 years. Sensitivity analyses were also conducted for all covariables.</p><p><strong>Results: </strong>The patients with SSNHL had a higher mean number of CP visits (0.71 within 1 year and 1.34 within 2 years) compared with control participants. CP was associated with increased odds of SSNHL, with an OR of 1.14 (95% CI, 1.10-1.19) for ≥1 CP visit, an OR of 1.09 (95% CI, 1.03-1.15) for ≥2 visits, and an OR of 1.09 (95% CI, 1.02-1.17) for ≥3 visits within 1 year. Furthermore, having experienced at least 1 visit for CP within 2 years was associated with 1.15 times greater odds of SSNHL (95% CI, 1.10-1.19). Higher rates of SSNHL were also observed in the subgroups of participants with underweight, overweight, and age ≥65 years, as well as those with comorbidities.</p><p><strong>Conclusion: </strong>CP was linked to an elevated incidence of SSNHL. Individuals with comorbidities, advanced age, or abnormal body weight were more likely to exhibit both CP and SSNHL.</p>\",\"PeriodicalId\":10318,\"journal\":{\"name\":\"Clinical and Experimental Otorhinolaryngology\",\"volume\":\" \",\"pages\":\"225-233\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12400140/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical and Experimental Otorhinolaryngology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.21053/ceo.2024.00297\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/3/24 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"OTORHINOLARYNGOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and Experimental Otorhinolaryngology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.21053/ceo.2024.00297","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/24 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
Relationship of Sudden Sensorineural Hearing Loss With History of Chronic Periodontitis.
Objectives: Chronic periodontitis (CP) has been linked to an increased risk of sudden sensorineural hearing loss (SSNHL). This study aimed to delineate the causal relationships between CP and SSNHL.
Methods: Data from participants aged 40 years or older in the Korean National Health Insurance Service-Health Screening Cohort from 2002 through 2019 were used. Data for 13,769 patients with SSNHL were collected and matched with those for 55,076 control participants based on demographic and socioeconomic variables. The incidence of CP before the onset of SSNHL was recorded. The odds ratios (ORs) for SSNHL based on CP history were calculated using conditional logistic regression. ORs were analyzed according to the frequency of CP, specifically ≥1, ≥2, and ≥3 clinic visits for CP within 1 year and ≥1 visit within 2 years. Sensitivity analyses were also conducted for all covariables.
Results: The patients with SSNHL had a higher mean number of CP visits (0.71 within 1 year and 1.34 within 2 years) compared with control participants. CP was associated with increased odds of SSNHL, with an OR of 1.14 (95% CI, 1.10-1.19) for ≥1 CP visit, an OR of 1.09 (95% CI, 1.03-1.15) for ≥2 visits, and an OR of 1.09 (95% CI, 1.02-1.17) for ≥3 visits within 1 year. Furthermore, having experienced at least 1 visit for CP within 2 years was associated with 1.15 times greater odds of SSNHL (95% CI, 1.10-1.19). Higher rates of SSNHL were also observed in the subgroups of participants with underweight, overweight, and age ≥65 years, as well as those with comorbidities.
Conclusion: CP was linked to an elevated incidence of SSNHL. Individuals with comorbidities, advanced age, or abnormal body weight were more likely to exhibit both CP and SSNHL.
期刊介绍:
Clinical and Experimental Otorhinolaryngology (Clin Exp Otorhinolaryngol, CEO) is an international peer-reviewed journal on recent developments in diagnosis and treatment of otorhinolaryngology-head and neck surgery and dedicated to the advancement of patient care in ear, nose, throat, head, and neck disorders. This journal publishes original articles relating to both clinical and basic researches, reviews, and clinical trials, encompassing the whole topics of otorhinolaryngology-head and neck surgery.
CEO was first issued in 2008 and this journal is published in English four times (the last day of February, May, August, and November) per year by the Korean Society of Otorhinolaryngology-Head and Neck Surgery. The Journal aims at publishing evidence-based, scientifically written articles from different disciplines of otorhinolaryngology field.
The readership contains clinical/basic research into current practice in otorhinolaryngology, audiology, speech pathology, head and neck oncology, plastic and reconstructive surgery. The readers are otolaryngologists, head and neck surgeons and oncologists, audiologists, and speech pathologists.