艾滋病病毒抗逆转录病毒治疗在纽约州的快速启动。

IF 2.7 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Christopher Wells, Redd Driver, Daniel Belanger, Elizabeth M. Boos, Jonas Barkevich, James M. Tesoriero
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引用次数: 0

摘要

在诊断出艾滋病毒后迅速开始抗逆转录病毒治疗(ART)是一种新方法,已证明对艾滋病毒护理有益。然而,这种方法在美国的使用率仍然很低。通过对纽约州卫生艾滋病研究所护理质量计划的艾滋病毒临床护理数据的回顾性审查,我们检查了2019年至2022年ART快速启动的变化,以评估快速启动模式在该州实现的程度。我们还确定了与延迟起始相关的患者水平因素,并检查了治疗起始时间与病毒载量抑制之间的关系。我们发现,在检查的几年中,快速启动稳步增加,但根据患者接受治疗的地点以及他们最初是由数据报告机构还是由外部医疗机构或测试中心诊断而有所不同。我们还发现,快速启动在几个患者层面的因素上有所不同,这也取决于患者最初是由数据报告机构还是由外部医疗机构或测试中心诊断的。最后,67.8%在HIV诊断当天开始抗逆转录病毒治疗的患者和69.7%在诊断后7天内开始抗逆转录病毒治疗的患者在诊断后91天内病毒被抑制,而在31天至91天内开始抗逆转录病毒治疗的患者中这一比例为42.9%。随着时间的推移,快速启动模式的使用率越来越高,快速启动与及时抑制病毒之间的密切联系表明,进一步采用这一战略可能会推动在实现“终结流行病”和卫生公平目标方面取得进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rapid Start of HIV Antiretroviral Therapy in New York State

Rapid start of antiretroviral therapy (ART) after an HIV diagnosis is a novel approach with demonstrated benefits for HIV care. However, utilization of this approach remains poor in the United States. Using retrospective reviews of HIV clinical care data from the New York State Department of Health AIDS Institute’s Quality of Care Program, we examined changes in rapid start of ART from 2019 to 2022 to assess the degree to which the rapid start model is being realized in the state. We also identified patient-level factors associated with delayed initiation and examined associations between time to treatment initiation and viral load suppression. We found that rapid initiation increased steadily across the years examined but differed depending on where patients received care and whether they were initially diagnosed by the data-reporting organization or by an external medical organization or testing center. We also found that rapid start varied across several patient-level factors, which also depended on whether patients were initially diagnosed by the data-reporting organization or by an external medical organization or testing center. Finally, 67.8% of patients who initiated ART on the same day of HIV diagnosis and 69.7% of patients who started ART within seven days of diagnosis were virally suppressed within 91 days of diagnosis, compared to 42.9% of patients who initiated ART between 31 and 91 days. Increased utilization of the rapid start model over time and strong associations between rapid start and timely viral suppression suggest that further uptake of this strategy would likely advance progress towards Ending the Epidemic and health equity goals.

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来源期刊
AIDS and Behavior
AIDS and Behavior Multiple-
CiteScore
6.60
自引率
13.60%
发文量
382
期刊介绍: AIDS and Behavior provides an international venue for the scientific exchange of research and scholarly work on the contributing factors, prevention, consequences, social impact, and response to HIV/AIDS. This bimonthly journal publishes original peer-reviewed papers that address all areas of AIDS behavioral research including: individual, contextual, social, economic and geographic factors that facilitate HIV transmission; interventions aimed to reduce HIV transmission risks at all levels and in all contexts; mental health aspects of HIV/AIDS; medical and behavioral consequences of HIV infection - including health-related quality of life, coping, treatment and treatment adherence; and the impact of HIV infection on adults children, families, communities and societies. The journal publishes original research articles, brief research reports, and critical literature reviews. provides an international venue for the scientific exchange of research and scholarly work on the contributing factors, prevention, consequences, social impact, and response to HIV/AIDS. This bimonthly journal publishes original peer-reviewed papers that address all areas of AIDS behavioral research including: individual, contextual, social, economic and geographic factors that facilitate HIV transmission; interventions aimed to reduce HIV transmission risks at all levels and in all contexts; mental health aspects of HIV/AIDS; medical and behavioral consequences of HIV infection - including health-related quality of life, coping, treatment and treatment adherence; and the impact of HIV infection on adults children, families, communities and societies. The journal publishes original research articles, brief research reports, and critical literature reviews.5 Year Impact Factor: 2.965 (2008) Section ''SOCIAL SCIENCES, BIOMEDICAL'': Rank 5 of 29 Section ''PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH'': Rank 9 of 76
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