基于四苯乙烯的手性AIEgen对映选择性检测手性酸

IF 4.1 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments Pub Date : 2025-03-22 DOI:10.1016/j.dyepig.2025.112781

Chunxuan Qi , Qingyang Li , Keyue Wei , Weiwei Zhao , Wangyan Zhang , Miao-Miao Chen , Xiuhua Zhang , Hai-Tao Feng

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引用次数: 0

摘要

对映体识别在药物分析和生命科学中是至关重要的，但仍然是一个重大的挑战。本文构建了(1R, 2R)-CHDA-2TPE和(1S, 2S)-CHDA-2TPE两种具有典型聚集诱导发射（AIE）特性的手性探针。手性探针对11种手性试剂具有较高的对映选择性。值得注意的是，探针与l-谷氨酸和d-谷氨酸的荧光强度比高达88.8。1H NMR滴定结果表明，氢键是对识别的响应。这些发现表明，合成的探针是分析手性化合物的有希望的候选者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Tetraphenylethylene based chiral AIEgen for enantioselective detection of chiral acids

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Tetraphenylethylene based chiral AIEgen for enantioselective detection of chiral acids

Enantioselective recognition is crucial in pharmaceutical analysis and life sciences but remains a significant challenge. Herein, we constructed two chiral probes named (1R, 2R)-CHDA-2TPE and (1S, 2S)-CHDA-2TPE, which exhibit typical aggregation-induced emission (AIE) properties. The chiral probes show high enantioselectivity to 11 kinds of chiral reagents. Notably, the fluorescence intensity ratio of the probe with l- and d-glutamic acid was up to 88.8. The ¹H NMR titration results suggested that the hydrogen bond is response for the recognition. These findings implied that the synthesized probes are promising candidates for analyzing chiral compounds.

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来源期刊

Dyes and Pigments 工程技术-材料科学：纺织

CiteScore

8.20

自引率

13.30%

发文量

933

审稿时长

33 days

期刊介绍： Dyes and Pigments covers the scientific and technical aspects of the chemistry and physics of dyes, pigments and their intermediates. Emphasis is placed on the properties of the colouring matters themselves rather than on their applications or the system in which they may be applied. Thus the journal accepts research and review papers on the synthesis of dyes, pigments and intermediates, their physical or chemical properties, e.g. spectroscopic, surface, solution or solid state characteristics, the physical aspects of their preparation, e.g. precipitation, nucleation and growth, crystal formation, liquid crystalline characteristics, their photochemical, ecological or biological properties and the relationship between colour and chemical constitution. However, papers are considered which deal with the more fundamental aspects of colourant application and of the interactions of colourants with substrates or media. The journal will interest a wide variety of workers in a range of disciplines whose work involves dyes, pigments and their intermediates, and provides a platform for investigators with common interests but diverse fields of activity such as cosmetics, reprographics, dye and pigment synthesis, medical research, polymers, etc.