Applying Mixed Methods to Enhance Health Equity in Research on Dementia and Cognitive Impairment.

ObjectivesThe NIA health disparities research framework details a life course approach that considers multilevel environmental, sociocultural, behavioral, and biological factors. Mixed methods are well-suited to study complex problems like structural racism, combining the benefits of generalizability with contextualization.MethodsWe draw on experience as faculty in the Mixed Methods Research Training Program for the Health Sciences to introduce mixed methods research on health equity and disparities in dementia and cognitive impairment.ResultsWe describe common reasons why health science investigators may use mixed methods, provide examples of mixed methods designs, and discuss challenges and practicalities of mixed methods research.DiscussionMany risk factors for dementia are modifiable, so the emphasis of research turns from description to intervention studies that enhance health equity. The information and insights acquired from the use of mixed methods are central in tailoring interventions to populations most affected by Alzheimer's disease and related dementias.