Nour B Odeh, Juan M Farina, Pete J Manchen, Kristen A Sell-Dottin, Bryan Barrus
{"title":"从长期使用二甲胺四环素到色素化的单尖瓣主动脉瓣:一个独特的单一病例。","authors":"Nour B Odeh, Juan M Farina, Pete J Manchen, Kristen A Sell-Dottin, Bryan Barrus","doi":"10.14797/mdcvj.1564","DOIUrl":null,"url":null,"abstract":"<p><p>We discuss the case of a 47-year-old female who presented to our institution with progressive exertional shortness of breath. Her history was notable for severe acne medicated with 100 mg oral daily minocycline for 2 years and a presumptive diagnosis of a bicuspid aortic valve. Investigations revealed severe aortic stenosis, prompting a decision for elective aortic valve repair. Intraoperatively, significant calcification of a unicuspid aortic valve, atypically blackened valve, and endocardium of the left ventricle and aorta were visualized.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"21 1","pages":"30-34"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927672/pdf/","citationCount":"0","resultStr":"{\"title\":\"From Chronic Use of Minocycline to Pigmented Unicuspid Aortic Valve: A Unique Single Case.\",\"authors\":\"Nour B Odeh, Juan M Farina, Pete J Manchen, Kristen A Sell-Dottin, Bryan Barrus\",\"doi\":\"10.14797/mdcvj.1564\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We discuss the case of a 47-year-old female who presented to our institution with progressive exertional shortness of breath. Her history was notable for severe acne medicated with 100 mg oral daily minocycline for 2 years and a presumptive diagnosis of a bicuspid aortic valve. Investigations revealed severe aortic stenosis, prompting a decision for elective aortic valve repair. Intraoperatively, significant calcification of a unicuspid aortic valve, atypically blackened valve, and endocardium of the left ventricle and aorta were visualized.</p>\",\"PeriodicalId\":39207,\"journal\":{\"name\":\"Methodist DeBakey cardiovascular journal\",\"volume\":\"21 1\",\"pages\":\"30-34\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-03-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927672/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Methodist DeBakey cardiovascular journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.14797/mdcvj.1564\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Methodist DeBakey cardiovascular journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14797/mdcvj.1564","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
From Chronic Use of Minocycline to Pigmented Unicuspid Aortic Valve: A Unique Single Case.
We discuss the case of a 47-year-old female who presented to our institution with progressive exertional shortness of breath. Her history was notable for severe acne medicated with 100 mg oral daily minocycline for 2 years and a presumptive diagnosis of a bicuspid aortic valve. Investigations revealed severe aortic stenosis, prompting a decision for elective aortic valve repair. Intraoperatively, significant calcification of a unicuspid aortic valve, atypically blackened valve, and endocardium of the left ventricle and aorta were visualized.