环境污染物与直肠癌：水污染的影响

IF 6.1 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Ecotoxicology and Environmental Safety Pub Date : 2025-03-23 DOI:10.1016/j.ecoenv.2025.118072

Yezhou Li , Zhe Piao , Xinbin Ge , Jinbao Feng , Denghua Sun , Jiayu Zhang

{"title":"环境污染物与直肠癌：水污染的影响","authors":"Yezhou Li , Zhe Piao , Xinbin Ge , Jinbao Feng , Denghua Sun , Jiayu Zhang","doi":"10.1016/j.ecoenv.2025.118072","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Water is a fundamental resource for life, and exposure to water contamination has far-reaching implications for an increased risk of tumor diseases.</div></div><div><h3>Methods</h3><div>Studies of rectal and colorectal cancer related to water contamination were identified from the published literature in the PUBMED databases from 2010 to 2024.</div></div><div><h3>Results</h3><div>This review provides a critical analysis of the current evidence, summarizing the association of water contamination, including industrial waste, pesticides, heavy metals, with rectal and colorectal cancer. It highlights their impact on rectal and colorectal cancer progression by underlying processes of DNA damage, chronic inflammation, and microbial contamination.</div></div><div><h3>Conclusion</h3><div>Rectal cancer is a significant global health concern with a strong association between environmental pollutants in water sources and increased incidence of rectal cancer. It is vital to identify how waster pollutants influence the development and progression of rectal cancer and formulate targeted preventive approaches and social interventions to decrease the disease's impact.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"294 ","pages":"Article 118072"},"PeriodicalIF":6.1000,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Environmental pollutants and rectal cancer: The impact of water contamination\",\"authors\":\"Yezhou Li , Zhe Piao , Xinbin Ge , Jinbao Feng , Denghua Sun , Jiayu Zhang\",\"doi\":\"10.1016/j.ecoenv.2025.118072\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Water is a fundamental resource for life, and exposure to water contamination has far-reaching implications for an increased risk of tumor diseases.</div></div><div><h3>Methods</h3><div>Studies of rectal and colorectal cancer related to water contamination were identified from the published literature in the PUBMED databases from 2010 to 2024.</div></div><div><h3>Results</h3><div>This review provides a critical analysis of the current evidence, summarizing the association of water contamination, including industrial waste, pesticides, heavy metals, with rectal and colorectal cancer. It highlights their impact on rectal and colorectal cancer progression by underlying processes of DNA damage, chronic inflammation, and microbial contamination.</div></div><div><h3>Conclusion</h3><div>Rectal cancer is a significant global health concern with a strong association between environmental pollutants in water sources and increased incidence of rectal cancer. It is vital to identify how waster pollutants influence the development and progression of rectal cancer and formulate targeted preventive approaches and social interventions to decrease the disease's impact.</div></div>\",\"PeriodicalId\":303,\"journal\":{\"name\":\"Ecotoxicology and Environmental Safety\",\"volume\":\"294 \",\"pages\":\"Article 118072\"},\"PeriodicalIF\":6.1000,\"publicationDate\":\"2025-03-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ecotoxicology and Environmental Safety\",\"FirstCategoryId\":\"93\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0147651325004087\",\"RegionNum\":2,\"RegionCategory\":\"环境科学与生态学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENVIRONMENTAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ecotoxicology and Environmental Safety","FirstCategoryId":"93","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0147651325004087","RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}

引用次数: 0

摘要

地下水是生命的基本资源，接触水污染对肿瘤疾病的风险增加具有深远的影响。方法从2010年至2024年PUBMED数据库中已发表的文献中筛选出与水污染相关的直肠癌和结直肠癌研究。结果本综述对现有证据进行了批判性分析，总结了包括工业废水、农药、重金属在内的水污染与直肠和结直肠癌的关系。它强调了它们通过DNA损伤、慢性炎症和微生物污染的潜在过程对直肠和结直肠癌进展的影响。结论直肠癌是全球关注的重大健康问题，水源环境污染物与直肠癌发病率增加有密切关系。确定废物污染物如何影响直肠癌的发展和进展，制定有针对性的预防方法和社会干预措施以减少疾病的影响至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Environmental pollutants and rectal cancer: The impact of water contamination

Background

Water is a fundamental resource for life, and exposure to water contamination has far-reaching implications for an increased risk of tumor diseases.

Methods

Studies of rectal and colorectal cancer related to water contamination were identified from the published literature in the PUBMED databases from 2010 to 2024.

Results

This review provides a critical analysis of the current evidence, summarizing the association of water contamination, including industrial waste, pesticides, heavy metals, with rectal and colorectal cancer. It highlights their impact on rectal and colorectal cancer progression by underlying processes of DNA damage, chronic inflammation, and microbial contamination.

Conclusion

Rectal cancer is a significant global health concern with a strong association between environmental pollutants in water sources and increased incidence of rectal cancer. It is vital to identify how waster pollutants influence the development and progression of rectal cancer and formulate targeted preventive approaches and social interventions to decrease the disease's impact.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Ecotoxicology and Environmental Safety 环境科学-毒理学

CiteScore

12.10

自引率

5.90%

发文量

1234

审稿时长

88 days

期刊介绍： Ecotoxicology and Environmental Safety is a multi-disciplinary journal that focuses on understanding the exposure and effects of environmental contamination on organisms including human health. The scope of the journal covers three main themes. The topics within these themes, indicated below, include (but are not limited to) the following: Ecotoxicology、Environmental Chemistry、Environmental Safety etc.