多发性骨髓瘤表现为下颌髁不明确的溶骨性病变：1例报告和文献复习

Q3 Dentistry

Oral and Maxillofacial Surgery Cases Pub Date : 2025-03-20 DOI:10.1016/j.omsc.2025.100394

Connor Capobianco , Mariela Padilla , Jungsuk Cho , Lauren Levi

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引用次数: 0

摘要

下颌髁的溶骨性病变可以代表多种不同的鉴别诊断，包括恶性肿瘤，如转移性疾病、朗格汉斯细胞组织细胞增多症（LCH）、骨肉瘤、软骨肉瘤和多发性骨髓瘤。本病例报告详细介绍了一名40岁男性，有3年的右颞下颌关节（TMJ）疼痛史，最初被误诊为颞下颌关节紊乱。综合影像学检查，包括锥形束计算机断层扫描（CBCT）、颌面计算机断层扫描（CT）和脑磁共振成像（MRI），显示在下颌骨、额骨和颈椎有广泛的溶骨性病变。ct引导活检证实浆细胞肿瘤的存在，导致多发性骨髓瘤的诊断。本病例报告强调在临床实践中需要保持警惕和全面的诊断方法，以避免在恶性肿瘤等严重潜在疾病的识别和治疗中出现延误。

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Multiple myeloma presenting as an ill-defined osteolytic lesion of the mandibular condyle: A case report and literature review

Osteolytic lesions of the mandibular condyle can represent a diverse range of differential diagnoses, including malignancies such as metastatic disease, Langerhans cell histiocytosis (LCH), osteosarcoma, chondrosarcoma, and multiple myeloma. This case report details a 40-year-old male with a 3-year history of right temporomandibular joint (TMJ) pain, initially misdiagnosed as temporomandibular disorder. Comprehensive imaging studies, including cone beam computed tomography (CBCT), maxillofacial computed tomography (CT), and brain magnetic resonance imaging (MRI), revealed extensive osteolytic lesions in the mandible, frontal bone, and cervical spine. A CT-guided biopsy confirmed the presence of a plasma cell neoplasm, leading to the diagnosis of multiple myeloma. This case report emphasizes the need for vigilance and comprehensive diagnostic approaches in clinical practice to avoid delays in the identification and treatment of serious underlying conditions such as malignancy.

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来源期刊

Oral and Maxillofacial Surgery Cases Medicine-Otorhinolaryngology

CiteScore

0.60

自引率

0.00%

发文量

审稿时长

69 days

期刊介绍： Oral and Maxillofacial Surgery Cases is a surgical journal dedicated to publishing case reports and case series only which must be original, educational, rare conditions or findings, or clinically interesting to an international audience of surgeons and clinicians. Case series can be prospective or retrospective and examine the outcomes of management or mechanisms in more than one patient. Case reports may include new or modified methodology and treatment, uncommon findings, and mechanisms. All case reports and case series will be peer reviewed for acceptance for publication in the Journal.