枸橼酸镓-68检测颅内中枢神经系统大的增强结核瘤失败：一个警示故事

IF 1.1 Q4 INFECTIOUS DISEASES

IDCases Pub Date : 2025-01-01 DOI:10.1016/j.idcr.2025.e02155

Selwyn Selva Kumar , Adrian Keith Noronha , Julie Hephzibah , Harshad Arvind Vanjare , Abi Manesh

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引用次数: 0

摘要

背景枸橼酸镓68是一种评估感染的新兴诊断工具。它在脑部感染中的表现尚不清楚。现有的中枢神经系统结核的诊断是不精确的。我们报告一位在右额叶有大的、活动性的、增强的、微生物学证实的结核瘤的患者，他接受了镓-68 PET CT检查。在结核性病变中未发现任何示踪剂摄取。结论：我们报告了使用Ga-68 PET CT检查中枢神经系统结核的谨慎性，并讨论了这种观察的潜在原因。

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Failure of Gallium-68 citrate to detect large, enhancing, intracerebral central nervous system tuberculomas: A cautionary tale

Background

Gallium-68 citrate is an emerging diagnostic tool for the evaluation of infections. Its performance in brain infections is unknown. The available diagnostics for central nervous system tuberculosis are imprecise.

Case presentation

We report a patient with large, active, enhancing, microbiologically confirmed tuberculomas in the right frontal lobe, who underwent Gallium-68 PET CT. It did not show any tracer uptake in the tuberculous lesions.