掺生物活性玻璃的仿生TPMS多孔羟基磷灰石骨支架：数字光加工增材制造、微观结构和性能

IF 8.1 2区材料科学 Q1 ENGINEERING, MANUFACTURING

Composites Part A: Applied Science and Manufacturing Pub Date : 2025-03-17 DOI:10.1016/j.compositesa.2025.108870

Wang Guo , Ping Li , Yuanheng Pang , Enyu Wang , Lei Zhao , Yanjian Huang , Shan Wang , Bin Liu , Hui You , Yu Long

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引用次数: 0

摘要

陶瓷骨支架的制备工艺和微观结构对其性能至关重要。本研究采用桌面级DLP，通过工艺优化制备TPMS结构的仿生羟基磷灰石（HA）支架，并通过掺杂58S生物玻璃调节其微观结构，提高其降解性能和生物性能。在烧结温度为1300℃、固含量为55%时，网格多孔支架的抗压强度为26.32 MPa，而Schwarz-P TPMS支架的抗压强度为33.52 MPa。XRD和SEM分析表明，58S在烧结过程中与HA发生反应，形成新相，改变了HA的微观结构，从而影响了HA支架的性能。改善了硅、钙、磷酸盐等生物活性离子的降解性能和释放速率，增强了支架的生物矿化和细胞反应。本研究证明了掺杂诱导的反应和相变在调节陶瓷骨支架的微观结构和性能方面的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Biomimetic TPMS porous hydroxyapatite bone scaffolds doped with bioactive glass: digital light processing additive manufacturing, microstructure and performance

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Biomimetic TPMS porous hydroxyapatite bone scaffolds doped with bioactive glass: digital light processing additive manufacturing, microstructure and performance

The preparation process and microstructure of ceramic bone scaffolds are crucial for their performance. In this study, we fabricated biomimetic hydroxyapatite (HA) scaffolds with TPMS structures using desktop-level DLP through process optimization and enhanced their degradation and biological performance by adjusting microstructure using 58S bioglass doping. The Grid porous scaffold exhibited an optimal compressive strength of 26.32 MPa at sintering temperature of 1300 °C and solid content of 55 wt%, while Schwarz-P TPMS scaffold achieved 33.52 MPa. XRD and SEM analyses revealed that 58S reacted with HA during sintering, forming new phases and altering the microstructure, thereby influencing the performance of the HA scaffolds. The degradation properties and release rates of bioactive ions, including silicon, calcium, and phosphate, were improved, enhancing the biomineralization and cell responses of the scaffolds. This study demonstrates the potential of doping-induced reactions and phase transitions in adjusting microstructure and performance of ceramic bone scaffolds.

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来源期刊

Composites Part A: Applied Science and Manufacturing 工程技术-材料科学：复合

CiteScore

15.20

自引率

5.70%

发文量

492

审稿时长

30 days

期刊介绍： Composites Part A: Applied Science and Manufacturing is a comprehensive journal that publishes original research papers, review articles, case studies, short communications, and letters covering various aspects of composite materials science and technology. This includes fibrous and particulate reinforcements in polymeric, metallic, and ceramic matrices, as well as 'natural' composites like wood and biological materials. The journal addresses topics such as properties, design, and manufacture of reinforcing fibers and particles, novel architectures and concepts, multifunctional composites, advancements in fabrication and processing, manufacturing science, process modeling, experimental mechanics, microstructural characterization, interfaces, prediction and measurement of mechanical, physical, and chemical behavior, and performance in service. Additionally, articles on economic and commercial aspects, design, and case studies are welcomed. All submissions undergo rigorous peer review to ensure they contribute significantly and innovatively, maintaining high standards for content and presentation. The editorial team aims to expedite the review process for prompt publication.