不孕症概述。

IF 2.1 4区 医学 Q3 ANDROLOGY
Awoniyi O Awonuga, Olivia G Camp, Mia M Biernat, Husam M Abu-Soud
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引用次数: 0

摘要

生儿育女是包括人类在内的动物的先天特征,是所有动物物种继续存在的必要条件。因此,对大多数妇女来说,不能怀孕或不能及时怀孕(称为不孕症)以使家族得以延续,在情感上是令人痛苦的。不孕症的定义是有争议的,因为它分为原发性和继发性。“低生育能力”一词的使用较为宽松,这使情况更加复杂。“低生育能力”指的是那些因怀孕所需时间超过自然时间而能力下降的夫妇,而不是那些因年龄不同而在6到12个月后完全无法怀孕的夫妇。不孕症的评估需要全面的男性和女性病史,对伴侣双方进行体格检查,并进行针对性的调查,以确定特定夫妇的不孕症原因。根据女性伴侣的年龄、调查结果、不孕症的原因、是否存在异常基因遗传、夫妇满意的怀孕率、可用的资源、夫妇实现活产的绝望程度以及他们想要承诺治疗的程度,适用于不孕症夫妇的各种治疗方法。不孕症治疗可能包括咨询和预期管理,自然或刺激周期的宫内人工授精,体外受精和/或ICSI。患有无精子症的男性将需要外科手术来获得体外受精/ ICSI的精子,但很少用于人工授精。本文综述了不孕症的病因、诊断、调查和治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Overview of infertility.

Having a child is an innate trait in animals, including humans, and is required for the continued existence of all animal species. Therefore, for most women, the inability to conceive or to do so in a timely fashion - termed infertility - to enable the continuation of the family line can be emotionally distressing. The definition of infertility is controversial because of its separation into primary and secondary. This is further complicated by the loosely used term subfertility, which relates to couples who have reduced ability because they take longer than the natural time to conceive, as opposed to those who are infertile and are entirely unable to conceive after 6 to 12 months, depending on age. Infertility evaluation requires a thorough male and female history, physical examination of both partners, and targeted investigation to determine the cause of infertility in a particular couple. Various treatments apply to infertile couples depending on the age of the female partner, the results of investigations, the reason for infertility, the presence of inheritance of abnormal genes, the pregnancy rates the couple is happy with, the resources available, how desperate the couple is to achieve a live birth, and how much they want to commit to treatment. Infertility treatment could include counseling and expectant management only, intrauterine insemination in a natural or stimulated cycle, and IVF and or ICSI. Men with azoospermia will need surgical options to retrieve sperm for IVF/ ICSI, but rarely for IUI. This review overviews infertility's etiology, diagnosis, investigations, and treatment.

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来源期刊
CiteScore
4.30
自引率
4.20%
发文量
27
审稿时长
>12 weeks
期刊介绍: Systems Biology in Reproductive Medicine, SBiRM, publishes Research Articles, Communications, Applications Notes that include protocols a Clinical Corner that includes case reports, Review Articles and Hypotheses and Letters to the Editor on human and animal reproduction. The journal will highlight the use of systems approaches including genomic, cellular, proteomic, metabolomic, bioinformatic, molecular, and biochemical, to address fundamental questions in reproductive biology, reproductive medicine, and translational research. The journal publishes research involving human and animal gametes, stem cells, developmental biology and toxicology, and clinical care in reproductive medicine. Specific areas of interest to the journal include: male factor infertility and germ cell biology, reproductive technologies (gamete micro-manipulation and cryopreservation, in vitro fertilization/embryo transfer (IVF/ET) and contraception. Research that is directed towards developing new or enhanced technologies for clinical medicine or scientific research in reproduction is of significant interest to the journal.
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