比较基因组学揭示了稻瘟病菌根真菌oididendron maus的金属敏感和金属耐受分离株的实质性差异。

IF 3.8 2区 生物学 Q2 MYCOLOGY
Stefania Daghino, Claude Murat, Stéphane De Mita, Elena Martino, Silvia Perotto
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引用次数: 0

摘要

一些能够形成ericoid菌根的耐重金属真菌分离物也可以使寄主植物具有更高的金属耐受性。其中一株真菌oididendron maius Zn已被鉴定,并确定了其耐金属表型的一些分子机制。在此,我们研究了O. maius Zn的有效基因组与O. maius耐金属和敏感分离株的基因组之间的差异,目的是确定可能参与耐金属表现的基因或基因间区域。将8株耐药菌株和10株敏感菌株的重测序基因组与参考文献O. maius Zn进行比对,得到357个基因模型,这些基因模型要么缺失,要么多态性太强,无法在敏感菌株的基因组中识别。这些区域包括与防御机制相关的功能基因和功能未知的基因。三分之一的预测基因模型被证明是高度多态性的,包括许多富集的氧化石墨烯术语,即DNA/RNA代谢和修饰、染色体/染色质组织、蛋白质生物合成、代谢和功能、能量消耗/转移和线粒体。总的来说,我们的研究结果表明,大孢子虫的耐受性表型可能来自多种遗传适应,而不是单一的机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative genomics reveals substantial divergence in metal sensitive and metal tolerant isolates of the ericoid mycorrhizal fungus Oidiodendron maius.

Some heavy metal tolerant fungal isolates capable of forming ericoid mycorrhiza can also confer increased metal tolerance to the host plant. One of these fungal isolates, Oidiodendron maius Zn, has been characterized and a few molecular mechanisms underlying its metal tolerant phenotype have been identified. Here, we investigate the genomic divergences between the available genome of O. maius Zn and the genomes of metal tolerant and sensitive isolates of O. maius, with the aim of identifying genes or intergenic regions possibly involved in the display of the tolerance. The resequenced genomes of 8 tolerant and 10 sensitive isolates were mapped on the reference, O. maius Zn, yielding 357 gene models from the reference that were either missing or too polymorphic to be identified in the genomes of the sensitive isolates. These regions included genes with functions related to defense mechanisms and with unknown functions. One third of the predicted gene models turned out to be highly polymorphic, including many enriched GO terms, i.e. DNA/RNA metabolism and modification, chromosome/chromatin organization, protein biosynthesis, metabolism and function, energy consumption/transfer and mitochondrion. Overall, our findings indicate that the tolerant phenotype in O. maius likely arises from multiple genetic adaptations rather than a singular mechanism.

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来源期刊
Mycorrhiza
Mycorrhiza 生物-真菌学
CiteScore
8.20
自引率
2.60%
发文量
40
审稿时长
6-12 weeks
期刊介绍: Mycorrhiza is an international journal devoted to research into mycorrhizas - the widest symbioses in nature, involving plants and a range of soil fungi world-wide. The scope of Mycorrhiza covers all aspects of research into mycorrhizas, including molecular biology of the plants and fungi, fungal systematics, development and structure of mycorrhizas, and effects on plant physiology, productivity, reproduction and disease resistance. The scope also includes interactions between mycorrhizal fungi and other soil organisms and effects of mycorrhizas on plant biodiversity and ecosystem structure. Mycorrhiza contains original papers, short notes and review articles, along with commentaries and news items. It forms a platform for new concepts and discussions, and is a basis for a truly international forum of mycorrhizologists from all over the world.
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