展望未来：你的生理性别可能会指导慢性疼痛的治疗。

IF 14.7 1区医学 Q1 NEUROSCIENCES

Neuron Pub Date : 2025-03-19 DOI:10.1016/j.neuron.2025.02.008

Marzia Malcangio, George Sideris-Lampretsas

引用次数: 0

摘要

神经性疼痛是一种临床问题，在女性中更为普遍。在本期的《神经元》杂志上，Fan等人发现了不同的性别依赖性通路驱动伤害感觉。重要的是，T细胞在雌性啮齿类动物中释放脂肪因子瘦素，而在雄性啮齿类动物中不释放，这为女性缓解疼痛提供了一种新的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

A look into the future: Your biological sex may guide chronic pain treatment.

Neuropathic pain constitutes a clinical problem more prevalent among women. In this issue of Neuron, Fan et al.¹ identify distinct sex-dependent pathways driving nociception. Importantly, T cells release the adipokine leptin in female but not male rodents, offering a novel approach for pain relief in women.

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来源期刊

Neuron 医学-神经科学

CiteScore

24.50

自引率

3.10%

发文量

382

审稿时长

1 months

期刊介绍： Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.