探索伤口愈合的新视野:综合分析。

IF 1.2 Q4 PHARMACOLOGY & PHARMACY
Saurabh Punia, Dheeraj Upadhyay, Pratiksha Srivastava, Sandeep Kumar Maurya, Umesh Kumar Patil, Meenakshi Gupta
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引用次数: 0

摘要

伤口愈合的生理过程是复杂的,涉及生物、分子和细胞途径之间的广泛联系。急性和慢性伤口每年影响全球数百万人,造成严重的社会经济负担,大大增加了截肢问题、住院时间延长和死亡率。尽管取得了巨大进展,但在老龄化人口中,糖尿病和抗生素耐药性等相关疾病使慢性伤口在临床上更具挑战性。科学技术的最新发展以及细胞和分子水平的研究为伤口愈合开辟了新的可能性,为新技术、新工艺和新信息奠定了基础。这篇综述提供了伤口愈合阶段的深入知识,创新的方法,以及成功治疗伤口修复的结合技术。这项研究揭示了与伤口愈合敷料相关的挑战,包括传统的、先进的和基于生物技术的敷料。此外,本研究还包括伤口修复的草药、伤口评估技术和实验性伤口愈合模型。该报告还包括新的治疗技术,例如能够实时监测和以可控速率给药的智能伤口敷料。最后,纳米机器人的使用是一种极具创造性和未来主义的方法,为伤口愈合增加了新的视野,同时也考虑了基于机器学习和人工智能(AI)的新分析工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploring New Horizons in Wound Healing: A Comprehensive Analysis.

The physiological process of wound healing is complicated and involves extensive connections between biological, molecular, and cellular pathways. Acute and chronic wounds pose a serious socioeconomic burden by impacting millions of people each year globally, which has significantly increased the problem of amputations, longer hospital stays, and mortality. Despite tremendous progress, in aging populations, associated conditions like diabetes and growing antibiotic resistance make chronic wounds even more clinically challenging. Recent developments in science and technology and research at cellular and molecular levels have opened up new possibilities for wound healing by laying the foundation for new technologies, techniques, and information. This review provides an in-depth knowledge of phases of wound healing, innovative methods, and combining technology for wound repair for successful therapies. This study reveals the associated challenges with wound healing dressings, including traditional, advanced, and biotechnology-based dressings. Moreover, this study also includes herbal remedies for wound repair, wound assessment techniques, and experimental wound healing models. This report additionally includes new treatment technologies, such as smart wound dressings capable of real-time monitoring and delivery of drugs at a controlled rate. Finally, an extremely inventive and futuristic approach that adds a new horizon in wound healing is the use of nanobots, and new analytical tools based on machine learning and artificial intelligence (AI) are also considered.

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CiteScore
4.30
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