{"title":"角膜经典:尼科尔斯、尼科尔斯和米切尔,“干眼症患者的体征和症状之间缺乏联系”(2004年)。","authors":"Karla Zadnik","doi":"10.1097/ICO.0000000000003857","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>Like all important areas of vision research, the field of dry eye has matured in the past 20 years. At the time this paper, currently the sixth most cited paper ever published in Cornea, was written by current leaders in the field, Kelly Nichols and Jason Nichols, their results challenged much of the accepted dogma. In a relevant small sample of clinic-based patients diagnosed with dry eye, they established the absence of important correlations between the patients' reported symptoms and diagnostic signs of dry eye, summarizing dry eye as a symptom-based disease.</p>","PeriodicalId":10710,"journal":{"name":"Cornea","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cornea Classic: Nichols, Nichols, and Mitchell, \\\"The Lack of Association Between Signs and Symptoms in Patients With Dry Eye Disease\\\" (2004).\",\"authors\":\"Karla Zadnik\",\"doi\":\"10.1097/ICO.0000000000003857\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Abstract: </strong>Like all important areas of vision research, the field of dry eye has matured in the past 20 years. At the time this paper, currently the sixth most cited paper ever published in Cornea, was written by current leaders in the field, Kelly Nichols and Jason Nichols, their results challenged much of the accepted dogma. In a relevant small sample of clinic-based patients diagnosed with dry eye, they established the absence of important correlations between the patients' reported symptoms and diagnostic signs of dry eye, summarizing dry eye as a symptom-based disease.</p>\",\"PeriodicalId\":10710,\"journal\":{\"name\":\"Cornea\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-03-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cornea\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/ICO.0000000000003857\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cornea","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/ICO.0000000000003857","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Cornea Classic: Nichols, Nichols, and Mitchell, "The Lack of Association Between Signs and Symptoms in Patients With Dry Eye Disease" (2004).
Abstract: Like all important areas of vision research, the field of dry eye has matured in the past 20 years. At the time this paper, currently the sixth most cited paper ever published in Cornea, was written by current leaders in the field, Kelly Nichols and Jason Nichols, their results challenged much of the accepted dogma. In a relevant small sample of clinic-based patients diagnosed with dry eye, they established the absence of important correlations between the patients' reported symptoms and diagnostic signs of dry eye, summarizing dry eye as a symptom-based disease.
期刊介绍:
For corneal specialists and for all general ophthalmologists with an interest in this exciting subspecialty, Cornea brings together the latest clinical and basic research on the cornea and the anterior segment of the eye. Each volume is peer-reviewed by Cornea''s board of world-renowned experts and fully indexed in archival format. Your subscription brings you the latest developments in your field and a growing library of valuable professional references.
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