Cesar Minelli, Esther Maria Langhi Chiozzini, Liliana Tiene Ujikawa, Geraldo Cassio Dos Reis, Millene Rodrigues Camilo, Octavio Marques Pontes-Neto
{"title":"在巴西mat<e:1> o的一项基于人群的研究中,首次卒中急性期预后不良的预测因素。","authors":"Cesar Minelli, Esther Maria Langhi Chiozzini, Liliana Tiene Ujikawa, Geraldo Cassio Dos Reis, Millene Rodrigues Camilo, Octavio Marques Pontes-Neto","doi":"10.1055/s-0045-1804924","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong> The data on predictors of poor outcomes for stroke patients in middle-income countries are lacking.</p><p><strong>Objective: </strong> To identify in the acute phase after a first-ever stroke (FES) predictors of a poor outcome within 3 months and 1 year in a population-based study in the town of Matão, state of São Paulo, Brazil.</p><p><strong>Methods: </strong> We prospectively investigated the characteristics of patients with FES in Matão, from a prospective study, in a population-based stroke registry, from 2015 to 2020. Poor outcome was defined as a modified Rankin scale (mRS) score of 3 to 6, assessed at 3 months and 1 year of follow-up. The association between predictors and poor outcome was analyzed by logistic regression analysis.</p><p><strong>Results: </strong> Of the 783 patients, the final sample consisted of 378 subjects for analysis. The mean age was 69.2(± 14.3) years, and 43.1% of patients were female. At 3 months and 1 year after a FES, 50.4% and 47.1% of stroke patients were classified as poor prognosis, respectively. Older age, female gender, hemiplegia, aphasia, subarachnoid hemorrhage, and comorbidities present in the acute phase were the predictors associated with a poor outcome.</p><p><strong>Conclusion: </strong> Non-modified and potentially modified predictors increase the risk of a poor FES prognosis in a population-based study from a middle-income country. Interventions focusing on these target populations and improving access to prevention and stroke management in the acute phase are necessary.</p>","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"83 2","pages":"1-7"},"PeriodicalIF":1.0000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Predictors of poor outcome in the acute phase after a first-ever stroke in a population-based study in Matão, Brazil.\",\"authors\":\"Cesar Minelli, Esther Maria Langhi Chiozzini, Liliana Tiene Ujikawa, Geraldo Cassio Dos Reis, Millene Rodrigues Camilo, Octavio Marques Pontes-Neto\",\"doi\":\"10.1055/s-0045-1804924\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong> The data on predictors of poor outcomes for stroke patients in middle-income countries are lacking.</p><p><strong>Objective: </strong> To identify in the acute phase after a first-ever stroke (FES) predictors of a poor outcome within 3 months and 1 year in a population-based study in the town of Matão, state of São Paulo, Brazil.</p><p><strong>Methods: </strong> We prospectively investigated the characteristics of patients with FES in Matão, from a prospective study, in a population-based stroke registry, from 2015 to 2020. Poor outcome was defined as a modified Rankin scale (mRS) score of 3 to 6, assessed at 3 months and 1 year of follow-up. The association between predictors and poor outcome was analyzed by logistic regression analysis.</p><p><strong>Results: </strong> Of the 783 patients, the final sample consisted of 378 subjects for analysis. The mean age was 69.2(± 14.3) years, and 43.1% of patients were female. At 3 months and 1 year after a FES, 50.4% and 47.1% of stroke patients were classified as poor prognosis, respectively. Older age, female gender, hemiplegia, aphasia, subarachnoid hemorrhage, and comorbidities present in the acute phase were the predictors associated with a poor outcome.</p><p><strong>Conclusion: </strong> Non-modified and potentially modified predictors increase the risk of a poor FES prognosis in a population-based study from a middle-income country. Interventions focusing on these target populations and improving access to prevention and stroke management in the acute phase are necessary.</p>\",\"PeriodicalId\":8694,\"journal\":{\"name\":\"Arquivos de neuro-psiquiatria\",\"volume\":\"83 2\",\"pages\":\"1-7\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Arquivos de neuro-psiquiatria\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1055/s-0045-1804924\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/3/19 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Arquivos de neuro-psiquiatria","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1055/s-0045-1804924","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/19 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
Predictors of poor outcome in the acute phase after a first-ever stroke in a population-based study in Matão, Brazil.
Background: The data on predictors of poor outcomes for stroke patients in middle-income countries are lacking.
Objective: To identify in the acute phase after a first-ever stroke (FES) predictors of a poor outcome within 3 months and 1 year in a population-based study in the town of Matão, state of São Paulo, Brazil.
Methods: We prospectively investigated the characteristics of patients with FES in Matão, from a prospective study, in a population-based stroke registry, from 2015 to 2020. Poor outcome was defined as a modified Rankin scale (mRS) score of 3 to 6, assessed at 3 months and 1 year of follow-up. The association between predictors and poor outcome was analyzed by logistic regression analysis.
Results: Of the 783 patients, the final sample consisted of 378 subjects for analysis. The mean age was 69.2(± 14.3) years, and 43.1% of patients were female. At 3 months and 1 year after a FES, 50.4% and 47.1% of stroke patients were classified as poor prognosis, respectively. Older age, female gender, hemiplegia, aphasia, subarachnoid hemorrhage, and comorbidities present in the acute phase were the predictors associated with a poor outcome.
Conclusion: Non-modified and potentially modified predictors increase the risk of a poor FES prognosis in a population-based study from a middle-income country. Interventions focusing on these target populations and improving access to prevention and stroke management in the acute phase are necessary.
期刊介绍:
Arquivos de Neuro-Psiquiatria is the official journal of the Brazilian Academy of Neurology. The mission of the journal is to provide neurologists, specialists and researchers in Neurology and related fields with open access to original articles (clinical and translational research), editorials, reviews, historical papers, neuroimages and letters about published manuscripts. It also publishes the consensus and guidelines on Neurology, as well as educational and scientific material from the different scientific departments of the Brazilian Academy of Neurology.
The ultimate goals of the journal are to contribute to advance knowledge in the areas of Neurology and Neuroscience, and to provide valuable material for training and continuing education for neurologists and other health professionals working in the area. These goals might contribute to improving care for patients with neurological diseases. We aim to be the best Neuroscience journal in Latin America within the peer review system.