在巴西mat o的一项基于人群的研究中,首次卒中急性期预后不良的预测因素。

IF 1 4区 医学 Q4 NEUROSCIENCES
Arquivos de neuro-psiquiatria Pub Date : 2025-02-01 Epub Date: 2025-03-19 DOI:10.1055/s-0045-1804924
Cesar Minelli, Esther Maria Langhi Chiozzini, Liliana Tiene Ujikawa, Geraldo Cassio Dos Reis, Millene Rodrigues Camilo, Octavio Marques Pontes-Neto
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引用次数: 0

摘要

背景:中等收入国家卒中患者预后不良预测因素的数据缺乏。目的:在巴西圣保罗州mat o镇的一项基于人群的研究中,确定首次中风后急性期(FES) 3个月和1年内不良预后的预测因素。方法:我们从2015年至2020年的一项基于人群卒中登记的前瞻性研究中,前瞻性地调查了mat o地区FES患者的特征。不良预后定义为改良Rankin量表(mRS)评分3 - 6分,在随访3个月和1年进行评估。采用logistic回归分析预测因子与不良预后的关系。结果:在783例患者中,最终样本包括378例受试者进行分析。平均年龄69.2(±14.3)岁,女性占43.1%。在FES后3个月和1年,50.4%和47.1%的脑卒中患者被归为预后不良。年龄较大、女性、偏瘫、失语、蛛网膜下腔出血和急性期的合并症是预后不良的预测因素。结论:在一项来自中等收入国家的基于人群的研究中,未经修改和可能修改的预测因子增加了FES预后不良的风险。针对这些目标人群的干预措施以及改善急性期卒中预防和管理的可及性是必要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Predictors of poor outcome in the acute phase after a first-ever stroke in a population-based study in Matão, Brazil.

Background:  The data on predictors of poor outcomes for stroke patients in middle-income countries are lacking.

Objective:  To identify in the acute phase after a first-ever stroke (FES) predictors of a poor outcome within 3 months and 1 year in a population-based study in the town of Matão, state of São Paulo, Brazil.

Methods:  We prospectively investigated the characteristics of patients with FES in Matão, from a prospective study, in a population-based stroke registry, from 2015 to 2020. Poor outcome was defined as a modified Rankin scale (mRS) score of 3 to 6, assessed at 3 months and 1 year of follow-up. The association between predictors and poor outcome was analyzed by logistic regression analysis.

Results:  Of the 783 patients, the final sample consisted of 378 subjects for analysis. The mean age was 69.2(± 14.3) years, and 43.1% of patients were female. At 3 months and 1 year after a FES, 50.4% and 47.1% of stroke patients were classified as poor prognosis, respectively. Older age, female gender, hemiplegia, aphasia, subarachnoid hemorrhage, and comorbidities present in the acute phase were the predictors associated with a poor outcome.

Conclusion:  Non-modified and potentially modified predictors increase the risk of a poor FES prognosis in a population-based study from a middle-income country. Interventions focusing on these target populations and improving access to prevention and stroke management in the acute phase are necessary.

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来源期刊
Arquivos de neuro-psiquiatria
Arquivos de neuro-psiquiatria 医学-精神病学
CiteScore
2.10
自引率
7.10%
发文量
262
审稿时长
4-8 weeks
期刊介绍: Arquivos de Neuro-Psiquiatria is the official journal of the Brazilian Academy of Neurology. The mission of the journal is to provide neurologists, specialists and researchers in Neurology and related fields with open access to original articles (clinical and translational research), editorials, reviews, historical papers, neuroimages and letters about published manuscripts. It also publishes the consensus and guidelines on Neurology, as well as educational and scientific material from the different scientific departments of the Brazilian Academy of Neurology. The ultimate goals of the journal are to contribute to advance knowledge in the areas of Neurology and Neuroscience, and to provide valuable material for training and continuing education for neurologists and other health professionals working in the area. These goals might contribute to improving care for patients with neurological diseases. We aim to be the best Neuroscience journal in Latin America within the peer review system.
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