Literature study on traditional Chinese medicine syndromes after renal transplantation.

Background: Kidney transplantation is the most effective means to treat patients with renal failure, but its postoperative problems such as rejection reactions, immunosuppressant poisoning, chronic transplant kidney nephropathy, etc. still have not been effectively solved. This study searched for literature on traditional Chinese medicine (TCM) syndromes after kidney transplantation in China, conducted statistical analysis of the results, and sought to identify the underlying patterns.

Aim: To understand the TCM syndromes after renal transplantation and associated rules and provide a theoretical basis for further clinical research.

Methods: The literature pertaining to TCM syndromes in renal transplantation, published in the China National Knowledge Infrastructure, Wanfang database, and WIP database from 1970 to 2021, was meticulously searched and comprehensively and statistically analyzed.

Results: Following the established inclusion and exclusion criteria, 13 studies were selected for analysis. Post-renal transplantation, no significant discrepancy was noted among the groups based on the location of TCM viscera. However, when categorized according to TCM pathogenic factors, the groups with spleen and kidney yang deficiency, as well as liver and kidney yin deficiency, exhibited a statistically significant difference in the frequency.

Conclusion: Currently, the research on TCM syndromes pertaining to renal transplantation is in its nascent phase. It is imperative to conduct a multicentric, large-scale survey of TCM syndromes subsequent to renal transplantation in the ensuing years.