Adalberto Batalha Megale, Nelson Wolosker, Vitoria Magliari Kalil, João Mário Nigro, Carolina Sciammarella Wakisaka, Bianca Oberhuber Dias, Marcelo Passos Teivelis, Marcelo Assis Rocha, Cynthia de Almeida Mendes
{"title":"主动脉钙评分预测主动脉髂血管重建术的早期结果。","authors":"Adalberto Batalha Megale, Nelson Wolosker, Vitoria Magliari Kalil, João Mário Nigro, Carolina Sciammarella Wakisaka, Bianca Oberhuber Dias, Marcelo Passos Teivelis, Marcelo Assis Rocha, Cynthia de Almeida Mendes","doi":"10.31744/einstein_journal/2025AO0527","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Calcium scores were evaluated in the lower limbs of patients with clinical limb ischemia after aortoiliac revascularization. The aortic calcium score was related to the short-term outcomes of amputation and subsequent revascularization. Similarly, the calcium score in below-the-knee arteries was associated with revascularization and amputation at 12 months. ■ The calcium score can be calculated using computed tomography angiography. ■ The aortic calcium score was associated with amputation and subsequent revascularization within 30 days. ■ The calcium score in below-the-knee arteries was higher in the patients who underwent subsequent revascularization and amputation at 12 months.</p><p><strong>Objective: </strong>To evaluate the association between lower limb artery calcium scores in preoperative computed tomography angiography and outcomes of patients with critical limb ischemia who underwent revascularization procedures in the aortoiliac segment.</p><p><strong>Methods: </strong>We retrospectively reviewed 14 interventions performed on 11 patients. The calcium score was calculated in segments of the aorta, iliac, femoropopliteal, and below-the-knee arteries. The evaluated outcomes included amputation, patency, death, subsequent revascularization, and readmission. Major adverse limb events were defined as amputation, subsequent revascularization, or readmission. The patients were followed through a 12-month period.</p><p><strong>Results: </strong>Higher aortic calcium scores were associated with amputation within 30 days (5,767.6 versus 805.3; p=0.02). Amputation during the first year correlated with a higher below-the-knee arteries calcium score (672.4 versus 163.25; p=0.04). Subsequent revascularization within 30 days was associated with a higher aortic calcium score (3,686.8 versus 645.2; p=0.008), while below-the-knee arteries calcium scores were associated with revascularization within 30 days (155.5 versus 817; p=0.05) and 12 months (158.875 versus 679.4; p=0.019). Readmissions within 1 year were more prevalent with higher below-the-knee arteries calcium scores (882.4 versus 32; p=0.011). Major adverse limb events were related to below-the-knee arteries calcium scores at 30 days (158.875 versus 679.4; p=0.019) and 1 year (12.3 versus 910.1; p=0.002).</p><p><strong>Conclusion: </strong>Below-the-knee arteries calcium score is a predictor of long-term revascularization, amputation, readmission, and major adverse limb events. The aortic calcium score was associated with amputation and subsequent revascularization within the first 30 days.</p>","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"23 ","pages":"eAO0527"},"PeriodicalIF":1.1000,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11908746/pdf/","citationCount":"0","resultStr":"{\"title\":\"Aortic calcium score predicts early outcomes in aortoiliac revascularization.\",\"authors\":\"Adalberto Batalha Megale, Nelson Wolosker, Vitoria Magliari Kalil, João Mário Nigro, Carolina Sciammarella Wakisaka, Bianca Oberhuber Dias, Marcelo Passos Teivelis, Marcelo Assis Rocha, Cynthia de Almeida Mendes\",\"doi\":\"10.31744/einstein_journal/2025AO0527\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Calcium scores were evaluated in the lower limbs of patients with clinical limb ischemia after aortoiliac revascularization. The aortic calcium score was related to the short-term outcomes of amputation and subsequent revascularization. Similarly, the calcium score in below-the-knee arteries was associated with revascularization and amputation at 12 months. ■ The calcium score can be calculated using computed tomography angiography. ■ The aortic calcium score was associated with amputation and subsequent revascularization within 30 days. ■ The calcium score in below-the-knee arteries was higher in the patients who underwent subsequent revascularization and amputation at 12 months.</p><p><strong>Objective: </strong>To evaluate the association between lower limb artery calcium scores in preoperative computed tomography angiography and outcomes of patients with critical limb ischemia who underwent revascularization procedures in the aortoiliac segment.</p><p><strong>Methods: </strong>We retrospectively reviewed 14 interventions performed on 11 patients. The calcium score was calculated in segments of the aorta, iliac, femoropopliteal, and below-the-knee arteries. The evaluated outcomes included amputation, patency, death, subsequent revascularization, and readmission. Major adverse limb events were defined as amputation, subsequent revascularization, or readmission. The patients were followed through a 12-month period.</p><p><strong>Results: </strong>Higher aortic calcium scores were associated with amputation within 30 days (5,767.6 versus 805.3; p=0.02). Amputation during the first year correlated with a higher below-the-knee arteries calcium score (672.4 versus 163.25; p=0.04). Subsequent revascularization within 30 days was associated with a higher aortic calcium score (3,686.8 versus 645.2; p=0.008), while below-the-knee arteries calcium scores were associated with revascularization within 30 days (155.5 versus 817; p=0.05) and 12 months (158.875 versus 679.4; p=0.019). Readmissions within 1 year were more prevalent with higher below-the-knee arteries calcium scores (882.4 versus 32; p=0.011). Major adverse limb events were related to below-the-knee arteries calcium scores at 30 days (158.875 versus 679.4; p=0.019) and 1 year (12.3 versus 910.1; p=0.002).</p><p><strong>Conclusion: </strong>Below-the-knee arteries calcium score is a predictor of long-term revascularization, amputation, readmission, and major adverse limb events. The aortic calcium score was associated with amputation and subsequent revascularization within the first 30 days.</p>\",\"PeriodicalId\":47359,\"journal\":{\"name\":\"Einstein-Sao Paulo\",\"volume\":\"23 \",\"pages\":\"eAO0527\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2025-03-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11908746/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Einstein-Sao Paulo\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31744/einstein_journal/2025AO0527\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Einstein-Sao Paulo","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31744/einstein_journal/2025AO0527","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
摘要
背景:对主动脉髂血管重建术后临床肢体缺血患者的下肢钙评分进行评估。主动脉钙评分与截肢和随后的血运重建术的短期预后有关。同样,在12个月时,膝关节以下动脉的钙评分与血运重建和截肢有关。■钙评分可以通过计算机断层血管造影计算。■主动脉钙评分与30天内截肢和随后的血运重建术相关。■在术后12个月接受血运重建术和截肢的患者中,膝关节以下动脉的钙评分较高。目的:评价危重肢体缺血患者行髂主动脉段血运重建术的术前ct血管造影中下肢动脉钙评分与预后的关系。方法:回顾性分析11例患者的14项干预措施。在主动脉、髂动脉、股腘动脉和膝下动脉段计算钙评分。评估的结果包括截肢、通畅、死亡、随后的血运重建术和再入院。主要肢体不良事件定义为截肢、随后的血运重建术或再入院。这些患者被随访了12个月。结果:较高的主动脉钙评分与30天内截肢相关(5,767.6对805.3;p = 0.02)。第一年截肢与较高的膝下动脉钙评分相关(672.4 vs 163.25;p = 0.04)。30天内的后续血运重建术与较高的主动脉钙评分相关(3686.8 vs 645.2;P =0.008),而膝盖以下动脉钙评分与30天内血运重建相关(155.5比817;P =0.05)和12个月(158.875 vs 679.4;p = 0.019)。1年内再入院的患者膝关节以下动脉钙评分较高(882.4比32;p = 0.011)。主要肢体不良事件与30天膝关节以下动脉钙评分相关(158.875比679.4;P =0.019)和1年(12.3 vs 910.1;p = 0.002)。结论:膝下动脉钙评分是长期血运重建、截肢、再入院和主要肢体不良事件的预测指标。主动脉钙评分与前30天内截肢和随后的血运重建术相关。
Aortic calcium score predicts early outcomes in aortoiliac revascularization.
Background: Calcium scores were evaluated in the lower limbs of patients with clinical limb ischemia after aortoiliac revascularization. The aortic calcium score was related to the short-term outcomes of amputation and subsequent revascularization. Similarly, the calcium score in below-the-knee arteries was associated with revascularization and amputation at 12 months. ■ The calcium score can be calculated using computed tomography angiography. ■ The aortic calcium score was associated with amputation and subsequent revascularization within 30 days. ■ The calcium score in below-the-knee arteries was higher in the patients who underwent subsequent revascularization and amputation at 12 months.
Objective: To evaluate the association between lower limb artery calcium scores in preoperative computed tomography angiography and outcomes of patients with critical limb ischemia who underwent revascularization procedures in the aortoiliac segment.
Methods: We retrospectively reviewed 14 interventions performed on 11 patients. The calcium score was calculated in segments of the aorta, iliac, femoropopliteal, and below-the-knee arteries. The evaluated outcomes included amputation, patency, death, subsequent revascularization, and readmission. Major adverse limb events were defined as amputation, subsequent revascularization, or readmission. The patients were followed through a 12-month period.
Results: Higher aortic calcium scores were associated with amputation within 30 days (5,767.6 versus 805.3; p=0.02). Amputation during the first year correlated with a higher below-the-knee arteries calcium score (672.4 versus 163.25; p=0.04). Subsequent revascularization within 30 days was associated with a higher aortic calcium score (3,686.8 versus 645.2; p=0.008), while below-the-knee arteries calcium scores were associated with revascularization within 30 days (155.5 versus 817; p=0.05) and 12 months (158.875 versus 679.4; p=0.019). Readmissions within 1 year were more prevalent with higher below-the-knee arteries calcium scores (882.4 versus 32; p=0.011). Major adverse limb events were related to below-the-knee arteries calcium scores at 30 days (158.875 versus 679.4; p=0.019) and 1 year (12.3 versus 910.1; p=0.002).
Conclusion: Below-the-knee arteries calcium score is a predictor of long-term revascularization, amputation, readmission, and major adverse limb events. The aortic calcium score was associated with amputation and subsequent revascularization within the first 30 days.