Transcatheter edge-to-edge mitral repair using MitraClip G4 for severe mitral regurgitation in an advanced elderly patient with Barlow's disease.

A 91-year-old male patient with a history of suspected Barlow's disease was diagnosed as mitral valve prolapse by physical examination for more than 10 years and chest distress for more than 1 month after exercise. Transthoracic echocardiography showed that the anterior leaflet of mitral valve was thickened and prolapsed with severe regurgitation, and transesophageal echocardiography further confirmed that the anterior and posterior leaflets of mitral valve were prolapsed with massive regurgitation (A1, A2, A3, P1 and P2 were all prolapsed). Transcatheter edge-to-edge mitral repair was performed with two Mitraclip XTWs. After 3 months of follow-up, the patient's cardiac function was significantly improved, and the degree of mitral regurgitation was mild.