中国多发性硬化症的诊断和治疗现状。

IF 4.1 2区 医学 Q1 CLINICAL NEUROLOGY
Current Opinion in Neurology Pub Date : 2025-06-01 Epub Date: 2025-03-19 DOI:10.1097/WCO.0000000000001359
Dongmei Jia, Fu-Dong Shi, Wei Jiang
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引用次数: 0

摘要

综述目的:本文综述了多发性硬化症(MS)在中国的最新进展,包括在卫生政策建议下的诊断和治疗挑战、研究和未来发展方向。最近的研究发现:在过去的几十年里,多发性硬化症在中国的患病率不断上升,由于人口众多,城乡之间存在明显的差异,多发性硬化症已成为一个重要的公共卫生问题。由于国家的多样性和不断变化的环境因素,中国MS患者的临床表现可能多种多样。诊断实践的进步,包括7T MRI放射评估的进步,提高了MS诊断的准确性。尽管引入了改善疾病的治疗药物,并为患者提供了更广泛的治疗选择的卫生保健政策的支持,但多项正在进行的研究工作和临床试验将提供更多的证据。正在进行的中国神经炎症疾病国家注册研究(NCT05154370)有望进一步加强中国多发性硬化症患者的管理。摘要:中国对多发性硬化症的认识和管理得到了改善,包括及时诊断和多种治疗选择。同时,研究努力和大规模队列研究显著提高了该领域的整体地位。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Multiple sclerosis in China: the current state of diagnosis and management.

Purpose of review: This comprehensive overview summarized the latest advances of multiple sclerosis (MS) in China, including the diagnostic and treatment challenges, research and future directions under health policy recommendations.

Recent findings: Given the rising prevalence of MS in China during the past decades, it has emerged as a significant public health concern due to the extensive population and pronounced disparities between urban and rural areas. The clinical manifestations of MS patients in China can be various due to the nation's diversity and evolving environmental factors. Advances in diagnostic practices, including the advances under 7T MRI radiological assessments, have enhanced the precision of MS diagnosis. Despite the introduction of disease-modifying therapeutic agents and the support of healthcare policies offering patients a wider range of treatment options, multiple ongoing research efforts and clinical trials will provide additional evidence. The ongoing China National Registry of Neuro-Inflammatory Diseases study (NCT05154370) holds promise for further enhancing the management of MS patients in China.

Summary: Improved recognition and management of MS in China have been facilitated, encompassing both prompt diagnosis and diverse treatment options. Simultaneously, research efforts and large-scale cohort studies have significantly advanced the overall status in this field.

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来源期刊
Current Opinion in Neurology
Current Opinion in Neurology 医学-临床神经学
CiteScore
8.60
自引率
0.00%
发文量
174
审稿时长
6-12 weeks
期刊介绍: ​​​​​​​​Current Opinion in Neurology is a highly regarded journal offering insightful editorials and on-the-mark invited reviews; covering key subjects such as cerebrovascular disease, developmental disorders, neuroimaging and demyelinating diseases. Published bimonthly, each issue of Current Opinion in Neurology introduces world renowned guest editors and internationally recognized academics within the neurology field, delivering a widespread selection of expert assessments on the latest developments from the most recent literature.
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