两剂量交叉碘平衡研究:中国幼儿碘需求。

IF 3.6 3区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Biological Trace Element Research Pub Date : 2025-10-01 Epub Date: 2025-03-18 DOI:10.1007/s12011-025-04573-6
Yan Song, Ying Zhang, Haohao Meng, Jie Liu, Wenwen Gu, Xiru Wang, Zhongna Sang
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引用次数: 0

摘要

中国目前使用的幼儿碘需要量可能被低估了。本研究旨在对中国幼儿进行碘平衡研究。我们采用双剂量交叉实验设计,依托当地饮用水中碘的浓度,通过调整幼儿每日对当地饮用水的摄取量来调整碘的摄入水平。我们测量了幼儿每日碘摄入量、排泄量和滞留量,并使用线性混合效应模型拟合总碘摄入量和碘滞留量之间的关系。这项研究涉及26名2-3岁的幼儿。根据幼儿每日总碘摄入量和碘平衡值,应用混合效应模型拟合回归曲线,得到回归方程:y = 0.214x - 16.68,由此计算幼儿EAR水平约为80µg/day, RNI水平约为110µg/day。在我们的研究中,我们预计目前碘营养状况下幼儿每日碘EAR和RNI水平的参考值分别约为80微克/天和110微克/天。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Two-Dose Crossover Iodine Balance Study: Iodine Requirements for Toddlers in China.

There is a possibility that the iodine requirement for toddlers currently used in China is underestimated. This study aimed to conduct an iodine balance study in Chinese toddlers. We used a two-dose crossover experimental design, relying on the local iodine concentration in drinking water, and adjusting the iodine intake level by adjusting the toddlers' daily consumption of local drinking water. We measured daily iodine intake, excretion, and retention in toddlers and used linear mixed-effects models were used to fit the relationship between total iodine intake and iodine retention. This study involved 26 toddlers aged 2-3 years. Based on the daily total iodine intake and iodine balance values of the toddlers, a mixed effects model was applied to fit the regression curve, and the regression equation was obtained: y = 0.214x - 16.68, from which the EAR and RNI levels of the toddlers were calculated to be approximately 80 µg/day, and 110 µg/day, respectively. In our study, we expected the reference values for daily iodine EAR and RNI levels in toddlers with their current iodine nutrition status to be about 80 µg/day and 110 µg/day, respectively.

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来源期刊
Biological Trace Element Research
Biological Trace Element Research 生物-内分泌学与代谢
CiteScore
8.70
自引率
10.30%
发文量
459
审稿时长
2 months
期刊介绍: Biological Trace Element Research provides a much-needed central forum for the emergent, interdisciplinary field of research on the biological, environmental, and biomedical roles of trace elements. Rather than confine itself to biochemistry, the journal emphasizes the integrative aspects of trace metal research in all appropriate fields, publishing human and animal nutritional studies devoted to the fundamental chemistry and biochemistry at issue as well as to the elucidation of the relevant aspects of preventive medicine, epidemiology, clinical chemistry, agriculture, endocrinology, animal science, pharmacology, microbiology, toxicology, virology, marine biology, sensory physiology, developmental biology, and related fields.
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