空间组学技术进展。

IF 10.7 2区材料科学 Q1 CHEMISTRY, PHYSICAL

Small Methods Pub Date : 2025-03-18 DOI:10.1002/smtd.202401171

Tianxiao Hui, Jian Zhou, Muchen Yao, Yige Xie, Hu Zeng

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引用次数: 0

摘要

快速发展的空间组学技术为我们深入了解生物体内细胞类型的多样性和功能提供了新的途径。与传统方法不同，空间组学技术使研究人员能够在细胞甚至亚细胞水平上解剖组织结构和功能之间的复杂关系。空间组学技术的应用为神经系统发育、器官发育、肿瘤微环境等关键生物过程的研究提供了新的视角。本文综述了空间组学技术的研究进展和策略，总结了空间组学技术在生物医学研究中的应用，并强调了空间组学技术在促进与发育和疾病相关的生命科学理解方面的作用。

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Advances in Spatial Omics Technologies.

Rapidly developing spatial omics technologies provide us with new approaches to deeply understanding the diversity and functions of cell types within organisms. Unlike traditional approaches, spatial omics technologies enable researchers to dissect the complex relationships between tissue structure and function at the cellular or even subcellular level. The application of spatial omics technologies provides new perspectives on key biological processes such as nervous system development, organ development, and tumor microenvironment. This review focuses on the advancements and strategies of spatial omics technologies, summarizes their applications in biomedical research, and highlights the power of spatial omics technologies in advancing the understanding of life sciences related to development and disease.

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来源期刊

Small Methods Materials Science-General Materials Science

CiteScore

17.40

自引率

1.60%

发文量

347

期刊介绍： Small Methods is a multidisciplinary journal that publishes groundbreaking research on methods relevant to nano- and microscale research. It welcomes contributions from the fields of materials science, biomedical science, chemistry, and physics, showcasing the latest advancements in experimental techniques. With a notable 2022 Impact Factor of 12.4 (Journal Citation Reports, Clarivate Analytics, 2023), Small Methods is recognized for its significant impact on the scientific community. The online ISSN for Small Methods is 2366-9608.