循环利用死细菌为巨噬细胞免疫代谢提供燃料

IF 27.7 1区医学 Q1 IMMUNOLOGY

Nature Immunology Pub Date : 2025-03-19 DOI:10.1038/s41590-025-02117-7

Shane M. O’Carroll, Luke A. J. O’Neill

引用次数: 0

摘要

巨噬细胞可以从它们吞噬的细菌中回收营养物质和代谢物。新的研究表明，这一过程在死亡细菌和活细菌之间是如何不同的，以及这种区别对调节免疫反应和巨噬细胞的免疫代谢的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Recycling dead bacteria to fuel macrophage immunometabolism

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Recycling dead bacteria to fuel macrophage immunometabolism

Macrophages can recycle nutrients and metabolites from bacteria that they phagocytose. New work is showing how this process can differ between dead and viable bacteria and the effect this distinction has on regulating immune responses and the immunometabolism of the macrophage.

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来源期刊

Nature Immunology 医学-免疫学

CiteScore

40.00

自引率

2.30%

发文量

248

审稿时长

4-8 weeks

期刊介绍： Nature Immunology is a monthly journal that publishes the highest quality research in all areas of immunology. The editorial decisions are made by a team of full-time professional editors. The journal prioritizes work that provides translational and/or fundamental insight into the workings of the immune system. It covers a wide range of topics including innate immunity and inflammation, development, immune receptors, signaling and apoptosis, antigen presentation, gene regulation and recombination, cellular and systemic immunity, vaccines, immune tolerance, autoimmunity, tumor immunology, and microbial immunopathology. In addition to publishing significant original research, Nature Immunology also includes comments, News and Views, research highlights, matters arising from readers, and reviews of the literature. The journal serves as a major conduit of top-quality information for the immunology community.