Potential role of coagulation markers in early detection of bone metastasis in gastric cancer: A critical review.

This letter to the editor involves the article published in the World Journal of Gastrointestinal Oncology. Bone metastasis (BM) in gastric cancer (GC) is uncommon but can be prevalent in autopsy studies. BM significantly impairs quality of life and is frequently underdiagnosed, as sensitive diagnostic tests are only performed after symptoms occur. Imaging is crucial for the diagnosis of BM but is not routinely used for screening and is expensive. Examining laboratory risk factors for BM in GC patients using multivariate analysis could be a more effective approach.