在脊柱畸形患者中生成定量计算机断层成像等效计算机断层成像解释报告。

Q2 Medicine
Journal of Bone Metabolism Pub Date : 2025-02-01 Epub Date: 2025-02-28 DOI:10.11005/jbm.24.801
Hyunbin Kim, Hyeon Su Kim, Shinjune Kim, Jun-Il Yoo
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引用次数: 0

摘要

背景:定量计算机断层扫描(QCT)是评估骨质疏松症和监测脊柱畸形的必要手段。“Clari-QCT”是一款使用人工智能分析传统计算机断层扫描(CT)并生成qcequivalent报告的软件。本研究旨在通过与传统QCT结果的比较来评估Clari-QCT的有效性,目的是验证脊柱畸形的新诊断工具。方法:本研究分析了仁荷大学医院18例患者的双能x线吸收仪、CT和QCT数据。评估了Clari-QCT软件从CT图像生成qct等效报告的能力。该软件处理腹部CT图像,计算指定切片的骨密度,并提供骨矿物质密度(BMD), t评分和z评分值。将患者分为正常、轻度和重度脊柱畸形组。用类内相关系数(Intraclass correlation coefficient, ICC)分析测量实际BMD值与预测值之间的一致性。结果:研究对象的平均年龄为64岁,平均体重指数为24.88。平均骨密度QCT为94.7 g/cm³,Clari- QCT为122.5 g/cm³,个体差异在4.9 ~ 61.8之间。T-score差异在0.16 ~ 6.86之间。ICC分析结果显示,各方法间的ICC1值为0.597,ICC2值为0.64,ICC3值为0.81,ICC1k、ICC2k、ICC3k值为0.748 ~ 0.895。结论:在正常和严重脊柱畸形组中,Clari-QCT与实际QCT测量结果吻合良好,但在轻度畸形患者中准确性降低。如果局限性得到解决,它可能成为监测脊柱畸形患者骨骼健康的有用工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Generate Quantitative Computed Tomography-Equivalent Computed Tomography Image Interpretation Reports in Patients with Spinal Deformities.

Background: Quantitative computed tomography (QCT) is essential for assessing osteoporosis and monitoring spinal deformities. "Clari-QCT," a software that uses artificial intelligence to analyze conventional computed tomography (CT) scans and produce QCTequivalent reports. This study aims to evaluate the effectiveness of Clari-QCT by comparing its results with traditional QCT, with the goal of validating new diagnostic tools for spinal deformities.

Methods: The study analyzed dual energy X-ray absorptiometry, CT, and QCT data from 18 patients at Inha University Hospital. Clari-QCT software was evaluated for its ability to generate QCT-equivalent reports from CT images. The software processes abdomen CT images, calculates bone density in designated slices, and provides bone mineral density (BMD), T-score, and Z-score values. Patients were classified into normal, mild, and severe spinal deformity groups. Intraclass correlation coefficient (ICC) analysis was used to measure the agreement between actual and predicted BMD values.

Results: The study included participants with an average age of 64 and a mean body mass index of 24.88. The average BMD was 94.7 g/cm³ by QCT and 122.5 g/cm³ by Clari- QCT, with individual differences ranging from 4.9 to 61.8. T-score discrepancies ranged from 0.16 to 6.86. ICC analysis showed moderate to high agreement between methods, with ICC1 values of 0.597, ICC2 of 0.64, ICC3 of 0.81, and ICC1k, ICC2k, ICC3k values ranging from 0.748 to 0.895.

Conclusions: Clari-QCT demonstrates good agreement with actual QCT measurements in normal and severe spinal deformity groups but shows reduced accuracy in patients with mild deformities. If the limitations are addressed, it could become a useful tool for monitoring bone health in patients with spinal deformities.

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来源期刊
Journal of Bone Metabolism
Journal of Bone Metabolism Medicine-Endocrinology, Diabetes and Metabolism
CiteScore
3.70
自引率
0.00%
发文量
23
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