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IF 2.5 3区医学 Q2 DERMATOLOGY

Dermatologic Surgery Pub Date : 2025-03-17 DOI:10.1097/DSS.0000000000004604

Trang T Vu, Laura C Soong, Reidar Hagtvedt, Christopher P Keeling

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引用次数: 0

摘要

背景：化脓性扁平湿疹（HS）是一种炎症，其治疗仍具有挑战性。切除术是一种外科技术，通过切除整个病变和窦道的 "真皮屋顶 "来达到治疗目的：我们进行了一项前瞻性研究，以评估切除术在治疗 Hurley I-III 期急性和慢性 HS 病变中的有效性和安全性。研究还量化了脱毛术作为阿达木单抗辅助治疗的作用，以及脱毛术对疼痛控制和生活质量（QoL）的影响：44名患者参加了一项开放式单臂研究，由一名临床医生进行治疗。结果：3个月和12个月后，患者的复发率明显降低：3个月和12个月后的复发率分别为10%（12/115）和11%（13/108）。脱毛是阿达木单抗患者的一种有效辅助治疗方法。Deroofing还能改善疼痛和QoL评分：Deroofing是一种安全有效的外科技术，可单独用于治疗Hurley I-III型疾病的急性和慢性复发/固定病灶，也可作为全身疗法的辅助手段。Deroofing术的复发率低，可减轻疼痛并改善QoL。

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Surgical Deroofing in the Management of Hidradenitis Suppurativa Alone or as an Adjunct to Medical Therapies.

Background: Hidradenitis suppurativa (HS) is an inflammatory condition that remains challenging to manage. Deroofing is a surgical technique whereby the "dermal roof" of the entire lesion and sinus tracts are removed.

Objective: A prospective study was conducted to assess the efficacy and safety of deroofing in the management of both acute and chronic HS lesions in Hurley Stage I-III disease. The role of deroofing as an adjunct to adalimumab and the impact of deroofing on pain control and quality of life (QoL) were also quantified.

Methods: Forty-four patients were enrolled in an open, single arm study treated by a single clinician. In total, 115 lesions were deroofed and patients were followed at 3 and 12 months after deroofing.

Results: At 3 and 12 months, the recurrence rate was 10% (12/115) and 11% (13/108), respectively. Deroofing is an effective adjunctive treatment for patients on adalimumab. Deroofing also improved pain and QoL scores.

Conclusion: Deroofing is a safe and effective surgical technique that can be used for acute and chronic recurrent/fixed lesions in Hurley I-III disease alone or as an adjunct to systemic therapies. Deroofing has a low recurrence rate, reduces pain, and improves QoL.

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来源期刊

Dermatologic Surgery 医学-皮肤病学

CiteScore

3.10

自引率

16.70%

发文量

547

期刊介绍： Exclusively devoted to dermatologic surgery, the Dermatologic Surgery journal publishes the most clinically comprehensive and up-to-date information in its field. This unique monthly journal provides today’s most expansive and in-depth coverage of cosmetic and reconstructive skin surgery and skin cancer through peer-reviewed original articles, extensive illustrations, case reports, ongoing features, literature reviews and correspondence. The journal provides information on the latest scientific information for all types of dermatologic surgery including: -Ambulatory phlebectomy- Blepharoplasty- Body contouring- Chemical peels- Cryosurgery- Curettage and desiccation- Dermabrasion- Excision and closure- Flap Surgery- Grafting- Hair restoration surgery- Injectable neuromodulators- Laser surgery- Liposuction- Microdermabrasion- Microlipoinjection- Micropigmentation- Mohs micrographic surgery- Nail surgery- Phlebology- Sclerotherapy- Skin cancer surgery- Skin resurfacing- Soft-tissue fillers. Dermatologists, dermatologic surgeons, plastic surgeons, oculoplastic surgeons and facial plastic surgeons consider this a must-read publication for anyone in the field.