抗生素-肠道微生物-泌尿肿瘤轴的前沿进展。

IF 5.9 1区生物学 Q2 CELL BIOLOGY

Cell Proliferation Pub Date : 2025-03-17 DOI:10.1111/cpr.70023

Jie Wang, Dengxiong Li, Ruicheng Wu, Dechao Feng

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引用次数: 0

摘要

肠道微生物群调节泌尿系统肿瘤。抗生素诱导生态失调，改变肿瘤进展/治疗：减少致癌物代谢，但损害免疫力。特定细菌增强免疫反应，对抗内分泌阻力。未来的研究应该揭示微生物与癌症之间的联系，并开发针对微生物组的治疗方法，以优化结果，同时保持多样性。

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Cutting-Edge Advancements in the Antibiotics-Gut Microbiota-Urinary Tumour Axis

Gut microbiota regulates urological tumors. Antibiotics induce dysbiosis, altering tumor progression/therapy: reducing carcinogen metabolism but impairing immunity. Specific bacteria enhance immune responses and combat endocrine resistance. Future research should unravel microbiota-cancer links and develop microbiome-targeted therapies to optimize outcomes while preserving diversity.

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来源期刊

Cell Proliferation 生物-细胞生物学

CiteScore

14.80

自引率

2.40%

发文量

198

审稿时长

1 months

期刊介绍： Cell Proliferation Focus: Devoted to studies into all aspects of cell proliferation and differentiation. Covers normal and abnormal states. Explores control systems and mechanisms at various levels: inter- and intracellular, molecular, and genetic. Investigates modification by and interactions with chemical and physical agents. Includes mathematical modeling and the development of new techniques. Publication Content: Original research papers Invited review articles Book reviews Letters commenting on previously published papers and/or topics of general interest By organizing the information in this manner, readers can quickly grasp the scope, focus, and publication content of Cell Proliferation.