一种高毒力和多重耐药的鸡沙门氏菌菌株在周龄肉鸡中引起的暴发。

IF 2.5 2区农林科学 Q1 VETERINARY SCIENCES

Avian Pathology Pub Date : 2025-04-07 DOI:10.1080/03079457.2025.2480800

Eric Santos Oliveira, Letícia Cury Rocha Veloso Arantes, Gabryel Bernardo Vieira de Lima, Victória Veiga Alves, Michelle de Paula Gabardo, Bertram Brenig, Vasco Azevedo, Flávia Figueira Aburjaile, Oliveiro Caetano de Freitas Neto, Roselene Ecco

{"title":"一种高毒力和多重耐药的鸡沙门氏菌菌株在周龄肉鸡中引起的暴发。","authors":"Eric Santos Oliveira, Letícia Cury Rocha Veloso Arantes, Gabryel Bernardo Vieira de Lima, Victória Veiga Alves, Michelle de Paula Gabardo, Bertram Brenig, Vasco Azevedo, Flávia Figueira Aburjaile, Oliveiro Caetano de Freitas Neto, Roselene Ecco","doi":"10.1080/03079457.2025.2480800","DOIUrl":null,"url":null,"abstract":"Research highlights: Salmonella Gallinarum infection in chicks resulted in a mortality rate of 42%.Chicks had unusual lesions such as haemorrhagic enteritis and interstitial pneumonia.Whole genome analysis of the SG isolate revealed exclusive antimicrobial resistance genes.Higher number of exclusive virulence genes were related to severe fowl typhoid in chicks.","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"1-7"},"PeriodicalIF":2.5000,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"An outbreak in week-old broiler chicks caused by a highly virulent and multidrug-resistant strain of Salmonella Gallinarum.\",\"authors\":\"Eric Santos Oliveira, Letícia Cury Rocha Veloso Arantes, Gabryel Bernardo Vieira de Lima, Victória Veiga Alves, Michelle de Paula Gabardo, Bertram Brenig, Vasco Azevedo, Flávia Figueira Aburjaile, Oliveiro Caetano de Freitas Neto, Roselene Ecco\",\"doi\":\"10.1080/03079457.2025.2480800\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Research highlights: Salmonella Gallinarum infection in chicks resulted in a mortality rate of 42%.Chicks had unusual lesions such as haemorrhagic enteritis and interstitial pneumonia.Whole genome analysis of the SG isolate revealed exclusive antimicrobial resistance genes.Higher number of exclusive virulence genes were related to severe fowl typhoid in chicks.\",\"PeriodicalId\":8788,\"journal\":{\"name\":\"Avian Pathology\",\"volume\":\" \",\"pages\":\"1-7\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-04-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Avian Pathology\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.1080/03079457.2025.2480800\",\"RegionNum\":2,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Avian Pathology","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1080/03079457.2025.2480800","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}

引用次数: 0

摘要

摘要鸡沙门氏菌是一种对家禽养殖业造成重大经济损失的细菌，通常感染成年禽类。本研究旨在描述鸡沙门氏菌（SG）菌株的不寻常组织学发现和遗传特征，该菌株从自然爆发中分离出来，影响了1500只出生第一周的肉鸡。为了证实诊断，对19只鸡进行了尸检、组织病理学和免疫组织化学检查，其中2只鸡进行了细菌分离，然后通过PCR、基因测序和基因组分析进行了证实。这次暴发显示了不寻常的大体和组织学病变：在肠道中，有不同程度的宏观出血，显微镜下，病变的特征是组织细胞性和嗜异性性跨壁斑疹炎；肺部有不同强度的组织细胞间质性肺炎。其他病变包括脾炎、心肌炎和肝炎。利用免疫组织化学（IHC）对上述所有器官中的沙门氏菌进行原位标记。根据病毒组和抗性组分析，将分离物的遗传谱与参考基因组进行比较，发现本次暴发的分离物含有36个独家毒力基因和6个独家抗微生物药物耐药性基因。这些基因改变可以解释在这些雏鸡身上观察到的严重全身病变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

An outbreak in week-old broiler chicks caused by a highly virulent and multidrug-resistant strain of Salmonella Gallinarum.

Research highlights: Salmonella Gallinarum infection in chicks resulted in a mortality rate of 42%.Chicks had unusual lesions such as haemorrhagic enteritis and interstitial pneumonia.Whole genome analysis of the SG isolate revealed exclusive antimicrobial resistance genes.Higher number of exclusive virulence genes were related to severe fowl typhoid in chicks.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Avian Pathology 农林科学-兽医学

CiteScore

4.50

自引率

10.70%

发文量

审稿时长

1 months

期刊介绍： Avian Pathology is the official journal of the World Veterinary Poultry Association and, since its first publication in 1972, has been a leading international journal for poultry disease scientists. It publishes material relevant to the entire field of infectious and non-infectious diseases of poultry and other birds. Accepted manuscripts will contribute novel data of interest to an international readership and will add significantly to knowledge and understanding of diseases, old or new. Subject areas include pathology, diagnosis, detection and characterisation of pathogens, infections of possible zoonotic importance, epidemiology, innate and immune responses, vaccines, gene sequences, genetics in relation to disease and physiological and biochemical changes in response to disease. First and subsequent reports of well-recognized diseases within a country are not acceptable unless they also include substantial new information about the disease or pathogen. Manuscripts on wild or pet birds should describe disease or pathogens in a significant number of birds, recognizing/suggesting serious potential impact on that species or that the disease or pathogen is of demonstrable relevance to poultry. Manuscripts on food-borne microorganisms acquired during or after processing, and those that catalogue the occurrence or properties of microorganisms, are unlikely to be considered for publication in the absence of data linking them to avian disease.