在社区药房无处方分发抗生素:一项模拟患者研究

IF 1.8 Q3 PHARMACOLOGY & PHARMACY
Thu Anh Do , Phuong Bao Quan , Thy Tran-Bao Le , Tuyen Thanh Du , Suong Thi-Thanh Duong , Kim Thai-Thien Nguyen , Khoi Ngoc Nguyen , Hoa Quoc Nguyen
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引用次数: 0

摘要

目的了解胡志明市社区药师(CPs)对普通感冒患者抗生素配药比例、咨询内容及相关因素。方法于2023年1 - 6月采用模拟病人(SP)法进行横断面研究。随机抽取胡志明市24个区352家社区药店。警司提供的投诉包括发烧、喉咙痛、咳嗽、吞咽困难、鼻塞,并要求治疗。采用贝叶斯模型平均来确定与抗生素分配实践相关的因素。结果352家纳入调查的药店中,药师建议和最终配发抗菌药物的比例分别为86.4%和83.0%。退烧药、皮质类固醇和止咳药也经常使用(分别为94.9%、90.1%和85.8%)。只有1.7%的CPs提供了服用抗生素的理由,8.8%的CPs建议服用整个疗程的抗生素。80.1%的CPs提供了配药剂量的咨询,1.7%提供了潜在药物不良反应的信息。连锁药店和城市地区的药剂师在没有处方的情况下分发抗生素的可能性低于独立药店的同行(OR = 0.32;95% CI: 0.17-0.59)和农村地区(OR = 0.53, 95% CI: 0.29-0.97)。结论药师无处方配药比例高,且咨询内容不足,特别是在独立药房和农村地区。这些问题突出表明需要提高CPs对抗生素耐药性和适当使用抗生素的知识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antibiotic dispensing without a prescription across community pharmacies: A simulated patient study

Objectives

This study aimed to investigate the proportion of antibiotics dispensed, counseling content, and factors associated with antibiotic dispensing for patients with common cold symptoms among community pharmacists (CPs) in Ho Chi Minh City (HCMC).

Methods

A cross-sectional study was conducted from January to June 2023 using a simulated patient (SP) method. A total of 352 community pharmacies across 24 districts in HCMC were randomly selected. The SP provided complaints including having fever, sore throat, cough, swallowing difficulty, stuffy nose and asked for treatment. Bayesian Model Averaging was undertaken to determine the factors associated with antibiotic dispensing practices.

Results

Of 352 enrolled pharmacies, the proportions of antibiotics suggested and eventually dispensed by CPs were 86.4 % and 83.0 %, respectively. Antipyretics, corticosteroids, and cough medicines were also frequently dispensed (94.9 %, 90.1 %, and 85.8 %, respectively). Only 1.7 % of the CPs provided reasons to take antibiotics, and 8.8 % advised to take the full course of antibiotics. While 80.1 % of CPs counseled on the dosage of medications dispensed, 1.7 % provided information regarding potential drug adverse reactions. CPs at chain pharmacies and in urban areas were less likely to dispense antibiotics without a prescription than their peers at independent pharmacies (OR = 0.32; 95 % CI: 0.17–0.59) and in rural areas (OR = 0.53, 95 % CI: 0.29–0.97).

Conclusion

A high proportion of CPs dispensing antibiotics without a prescription along with inadequate counseling content, especially at independent pharmacies and in rural areas was recorded. These issues hightlight the need to improve CPs' knowledge regarding antibiotic resistance and appropriate antibiotic use.
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来源期刊
CiteScore
1.60
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