Electrochemical Borylation of C−C and C−Het Bonds

Recently, electrochemical methods have been harnessed as a transition metal-free strategy for borylation reactions in the synthesis of organoboron compounds. This article reviews the electrochemical borylation of C−C and C−Het bonds, offering a systematic discussion of C−C, C−N, C−O, and C−S bond borylation reactions. These transformations are applied to substrates including ammonium salts, aryl azo sulfones, carboxylic acids, arylhydrazines, nitroarenes, alcohols, and thioethers, showcasing broad compatibility. Additionally, the review discusses reaction mechanisms, scalability, and practical applications of these electrochemical strategies. The article concludes by outlining future research directions for electrochemical borylation reactions, aiming at expending their applications in incorporating boron into a wider array of organic compounds, including the challenging unactivated C−Het and C−F bond borylations.