封面专题：用于双模式硝基还原酶传感的内质网靶向延迟荧光探针（《亚洲化学杂志》6/2025）

IF 3.5 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemistry - An Asian Journal Pub Date : 2025-03-18 DOI:10.1002/asia.202580603

V. T. K. Shradha, Subhadeep Das, Abhijit Patra

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Cover Feature: Endoplasmic Reticulum-Targeting Delayed Fluorescent Probe for Dual-mode Nitroreductase Sensing (Chem. Asian J. 6/2025)

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Cover Feature: Endoplasmic Reticulum-Targeting Delayed Fluorescent Probe for Dual-mode Nitroreductase Sensing (Chem. Asian J. 6/2025)

The study highlights an innovative approach to developing a highly selective delayed fluorescent probe for the dual-mode detection of a cancer hallmark within the endoplasmic reticulum (ER, depicted as a greenish-blue structure). The ER-specific probe, designed for selective detection of nitroreductase (NTR, shown in orange), is initially in a non-fluorescent state (grey). Upon interacting with NTR, the probe activates, emitting green fluorescence and long-lived emission, enabling intracellular detection through luminescence and time-resolved imaging modes symbolized by clock icons. More details can be found in article number e202401226 by Abhijit Patra and co-workers.

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来源期刊

Chemistry - An Asian Journal 化学-化学综合

CiteScore

7.00

自引率

2.40%

发文量

535

审稿时长

1.3 months

期刊介绍： Chemistry—An Asian Journal is an international high-impact journal for chemistry in its broadest sense. The journal covers all aspects of chemistry from biochemistry through organic and inorganic chemistry to physical chemistry, including interdisciplinary topics. Chemistry—An Asian Journal publishes Full Papers, Communications, and Focus Reviews. A professional editorial team headed by Dr. Theresa Kueckmann and an Editorial Board (headed by Professor Susumu Kitagawa) ensure the highest quality of the peer-review process, the contents and the production of the journal. Chemistry—An Asian Journal is published on behalf of the Asian Chemical Editorial Society (ACES), an association of numerous Asian chemical societies, and supported by the Gesellschaft Deutscher Chemiker (GDCh, German Chemical Society), ChemPubSoc Europe, and the Federation of Asian Chemical Societies (FACS).