{"title":"泰国鱼过敏儿童的致敏特征","authors":"Supaluk Tangvalelerd, Surapon Piboonpocanun, Unchalee Raungsirarak, Manaporn Sirichuwong, Pakit Vichyanond, Punchama Pacharn","doi":"10.15586/aei.v53i2.1209","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Fish allergies are common food allergies, and in Thailand, the prevalence of fish allergies in children ranges from 0.29% to 1.1%. Common fish allergens include parvalbumin, enolase, and aldolase.</p><p><strong>Method: </strong>This cross-sectional study included children with immunoglobulin E (IgE)-mediated fish allergies. The diagnosis was based on clinical history with a positive skin prick test (SPT) and/or specific IgE (sIgE). Serum IgE binding profiles to allergens in fish extracts were analyzed.</p><p><strong>Result: </strong>Eleven children, with a median age of 3 years, were recruited; the median age of onset was 1.25 years. Cutaneous symptoms were the most frequent clinical manifestation (63.6%). Tilapia and catfish were the most common triggers. All participants showed positive SPT and/or sIgE results for fish species. The immunoblot analysis revealed IgE binding to 40-50 kDa protein in all participants, while only seven participants (63.6%) showed IgE binding to the 11 kDa protein.</p><p><strong>Conclusion: </strong>Tilapia and catfish are the most common triggers of fish allergies in Thai children. The 40-50 kDa proteins were identified as a major fish allergen in tested cohort.</p>","PeriodicalId":7536,"journal":{"name":"Allergologia et immunopathologia","volume":"53 2","pages":"108-112"},"PeriodicalIF":2.5000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sensitization profile of Thai children with fish allergy.\",\"authors\":\"Supaluk Tangvalelerd, Surapon Piboonpocanun, Unchalee Raungsirarak, Manaporn Sirichuwong, Pakit Vichyanond, Punchama Pacharn\",\"doi\":\"10.15586/aei.v53i2.1209\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Fish allergies are common food allergies, and in Thailand, the prevalence of fish allergies in children ranges from 0.29% to 1.1%. Common fish allergens include parvalbumin, enolase, and aldolase.</p><p><strong>Method: </strong>This cross-sectional study included children with immunoglobulin E (IgE)-mediated fish allergies. The diagnosis was based on clinical history with a positive skin prick test (SPT) and/or specific IgE (sIgE). Serum IgE binding profiles to allergens in fish extracts were analyzed.</p><p><strong>Result: </strong>Eleven children, with a median age of 3 years, were recruited; the median age of onset was 1.25 years. Cutaneous symptoms were the most frequent clinical manifestation (63.6%). Tilapia and catfish were the most common triggers. All participants showed positive SPT and/or sIgE results for fish species. The immunoblot analysis revealed IgE binding to 40-50 kDa protein in all participants, while only seven participants (63.6%) showed IgE binding to the 11 kDa protein.</p><p><strong>Conclusion: </strong>Tilapia and catfish are the most common triggers of fish allergies in Thai children. The 40-50 kDa proteins were identified as a major fish allergen in tested cohort.</p>\",\"PeriodicalId\":7536,\"journal\":{\"name\":\"Allergologia et immunopathologia\",\"volume\":\"53 2\",\"pages\":\"108-112\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Allergologia et immunopathologia\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.15586/aei.v53i2.1209\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"ALLERGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Allergologia et immunopathologia","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.15586/aei.v53i2.1209","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"ALLERGY","Score":null,"Total":0}
Sensitization profile of Thai children with fish allergy.
Introduction: Fish allergies are common food allergies, and in Thailand, the prevalence of fish allergies in children ranges from 0.29% to 1.1%. Common fish allergens include parvalbumin, enolase, and aldolase.
Method: This cross-sectional study included children with immunoglobulin E (IgE)-mediated fish allergies. The diagnosis was based on clinical history with a positive skin prick test (SPT) and/or specific IgE (sIgE). Serum IgE binding profiles to allergens in fish extracts were analyzed.
Result: Eleven children, with a median age of 3 years, were recruited; the median age of onset was 1.25 years. Cutaneous symptoms were the most frequent clinical manifestation (63.6%). Tilapia and catfish were the most common triggers. All participants showed positive SPT and/or sIgE results for fish species. The immunoblot analysis revealed IgE binding to 40-50 kDa protein in all participants, while only seven participants (63.6%) showed IgE binding to the 11 kDa protein.
Conclusion: Tilapia and catfish are the most common triggers of fish allergies in Thai children. The 40-50 kDa proteins were identified as a major fish allergen in tested cohort.
期刊介绍：
Founded in 1972 by Professor A. Oehling, Allergologia et Immunopathologia is a forum for those working in the field of pediatric asthma, allergy and immunology. Manuscripts related to clinical, epidemiological and experimental allergy and immunopathology related to childhood will be considered for publication. Allergologia et Immunopathologia is the official journal of the Spanish Society of Pediatric Allergy and Clinical Immunology (SEICAP) and also of the Latin American Society of Immunodeficiencies (LASID). It has and independent international Editorial Committee which submits received papers for peer-reviewing by international experts. The journal accepts original and review articles from all over the world, together with consensus statements from the aforementioned societies. Occasionally, the opinion of an expert on a burning topic is published in the "Point of View" section. Letters to the Editor on previously published papers are welcomed. Allergologia et Immunopathologia publishes 6 issues per year and is included in the major databases such as Pubmed, Scopus, Web of Knowledge, etc.
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