基于溶菌酶/气管抗菌肽的组织特异性表达抗菌质粒在治疗小鼠乳腺炎中显示出广谱抗菌活性（ad . Biology 3/2025）

IF 3.2 3区生物学 Q3 MATERIALS SCIENCE, BIOMATERIALS

Advanced biology Pub Date : 2025-03-17 DOI:10.1002/adbi.202570095

Yi Yang, Yining Meng, Daijie Chen, Ping Hou, Zhipeng Zhang, Wenqiang Cao, Ye Meng, Qianwen Zhang, Runyan Tu, Xiaoli Hao, Aijian Qin, Shaobin Shang, Zhangping Yang

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引用次数: 0

摘要

细菌感染的非抗生素治疗由于抗生素耐药性的增加，细菌性疾病的治疗变得越来越具有挑战性。Yi Yang， Yining孟和同事开发了基于溶菌酶/气管抗菌肽的组织特异性表达抗菌质粒，减轻了小鼠的乳腺炎，并且具有良好的安全性。他们的工作提供了有希望的抗生素替代品。详情请参阅编号2400132的文章。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Lysozyme/Tracheal Antimicrobial Peptide-Based Tissue-Specific Expression Antimicrobial Plasmids Show Broad-Spectrum Antibacterial Activities in the Treatment of Mastitis in Mice (Adv. Biology 3/2025)

查看原文本刊更多论文

Lysozyme/Tracheal Antimicrobial Peptide-Based Tissue-Specific Expression Antimicrobial Plasmids Show Broad-Spectrum Antibacterial Activities in the Treatment of Mastitis in Mice (Adv. Biology 3/2025)

Non-Antibiotic Therapies for Bacterial Infections

The treatment of bacterial diseases is becoming more and more challenging due to the concern of increasing antibiotic resistance. Yi Yang, Yining Meng, and co-workers have developed lysozyme/tracheal antimicrobial peptide-based tissue-specific expression antimicrobial plasmids, alleviating mastitis in mice with a favorable safety profile. Their work offers promising antibiotic alternatives. More details can be found in article number 2400132.

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来源期刊

Advanced biology Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

6.60

自引率

0.00%

发文量

130