A. P. Kuvirchenkova, T. N. Goleva, D. V. Sukhinov, Ya. E. Sergeeva, R. G. Vasilov
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引用次数: 0
摘要
c -藻蓝蛋白是一种水溶性的光收集色素-蓝藻光合机构的蛋白质复合物,具有抗氧化、抗肿瘤和抗炎作用,经常用于医学研究。本文研究了从platarthrospira蓝藻中分离的c -藻蓝蛋白对大鼠肝脏线粒体生物能量参数的影响。结果表明,c -藻蓝蛋白对离体大鼠肝线粒体不表现出解偶联、去极化或抑制呼吸链作用,不降低ATP合成速率,但表现出较强的抗氧化作用。
C-phycocyanin, a water soluble light-harvesting pigment-protein complex of the cyanobacteria photosynthetic apparatus, demonstrates antioxidant, antitumor, and anti-inflammatory effects, and is often used in medical studies. In this work, the effect of C-phycocyanin isolated from the cyanobacterium Arthrospira platensis on the bioenergetic parameters of rat-liver mitochondria is examined. It is shown that C-phycocyanin does not exhibit uncoupling, depolarization or inhibition of the respiratory chain action for isolated rat-liver mitochondria, does not reduce the rate of ATP synthesis, but does exhibit a strong antioxidant effect.
期刊介绍:
Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.