Varsha D Badal, Laura M Campbell, Colin A Depp, Emma M Parrish, Robert A Ackerman, Raeanne C Moore, Philip D Harvey, Amy E Pinkham
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引用次数: 0
摘要
目的：主观认知抱怨（SCC）是轻度认知障碍（MCI）中常见的临床症状，但与情绪状态相互交织。通过对 SCC 的生态矩阵评估（EMA）和网络分析，我们试图揭示情绪与 SCC 之间的联系，以及这些联系如何因是否存在 MCI 而有所不同：设计：我们使用 EMA 收集密集的纵向数据。设计：我们使用 EMA 收集密集的纵向数据，除了在总体水平上分析数据以估计情绪和 SCC 变量的人际关联外，我们还使用时间序列分析来估计变量之间的同期和时滞关系：环境：在受试者的自然环境中进行 EMA 调查和移动认知测试：样本包括100名参与者，其中48人认知正常（NC），52人患有MCI：参与者完成为期 30 天的 EMA 方案，其中每天 3 次对 SCC 和情绪进行抽样调查：结果：在 MCI 患者中，SCC（通过 EMA 测量）与实验室中的标准 SCC 测量之间存在显著关联，而在 NC 患者中则不存在这种关联。尽管SCC的严重程度在平均水平上没有差异，但与MCI相比，NC患者的负性情绪（由EMA测量）与SCC之间存在很强的关联：EMA也许是测量MCI中SCC的一种有用而有效的方法。网络分析表明，消极情绪与后来的SCC有关。与 MCI 患者相比，NC 患者的这一发现更为明显。MCI患者的负性情绪与SCC之间的联系减弱，其原因值得进一步研究。
Dynamic influence of mood on subjective cognitive complaints in mild cognitive impairment: A time series network analysis approach.
Objectives: Subjective cognitive complaints (SCC) are common and clinically relevant in mild cognitive impairment (MCI) but are intertwined with mood states. Using Ecological Momentary Assessment (EMA) of SCC and network analyses we sought to uncover the links between mood and SCC and how these links may vary by the presence or absence of MCI.
Design: We used EMA to collect intensive longitudinal data. In addition to analyzing the data at an aggregate level to estimate between-person associations of affect and SCC variables, we used time series analyses to estimate contemporaneous and time-lagged relations between the variables.
Setting: EMA survey and mobile cognitive testing in subjects' natural environments.
Participants: The sample included 100 participants, 48 with Normal Cognition (NC), and 52 with MCI.
Measurements: Participants completed 30-day EMA protocols in which surveys sampling SCC and moods were delivered 3 times per day.
Results: The association between SCC (as measured by EMA) and standard in-lab measures of SCC was significant in MCI, but not in NC. Despite no average level differences in severity of SCC, there was a strong association between negative affect (as measured by EMA) with SCC in NCs compared to MCI.
Conclusions: EMA maybe a useful and valid approach to measuring SCCs in MCI. Network analyses indicated that negative affect was linked with later SCCs. This finding was strong in persons with NC than in persons with MCI. The basis of the attenuated association between negative affect and SCCs in MCI deserves further study.
期刊介绍：
A highly respected, multidisciplinary journal, International Psychogeriatrics publishes high quality original research papers in the field of psychogeriatrics. The journal aims to be the leading peer reviewed journal dealing with all aspects of the mental health of older people throughout the world. Circulated to over 1,000 members of the International Psychogeriatric Association, International Psychogeriatrics also features important editorials, provocative debates, literature reviews, book reviews and letters to the editor.
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