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IF 1.6 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques Pub Date : 2025-03-16 DOI:10.1111/echo.70091

Bang Du, Shuxin Liang, Rui Zhang, Wenjia Shi, Ruonan Wang, Yahong Qin, Aiai Chu

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引用次数: 0

摘要

背景阻塞性睡眠呼吸暂停综合征（OSAS）患者的右心室（RV）舒张功能和右心房（RA）功能特征不明显，但可能影响运动能力。我们旨在评估阻塞性睡眠呼吸暂停综合征患者的右心房功能和右心室舒张功能，并研究它们与运动能力的关系。方法前瞻性地对 53 名 OSAS 患者和 30 名年龄和性别匹配的对照组患者进行超声心动图检查和心肺运动测试，以研究 RV 舒张功能、RA 功能和运动能力。结果三尖瓣E/e′比值（TV E/e′）和等容舒张时间（IVRT）升高，RV TDI e′速度降低，表明重度OSAS患者的RV舒张功能发生了改变。TV E/e′与峰值 VO2 有一定的相关性（r = -0.334，p < 0.01）。严重 OSAS 患者的 RA 总排空分数、RA 被动排空分数和 RA 储库应变（RARS）均受损，RARS 与峰值摄氧量（VO2）相关（储库功能的 r = 0.451，p < 0.01）。结论 OSAS 患者 RA 功能和 RV 舒张功能的改变与运动能力受损有关。RA 功能和 RV 舒张功能与运动能力的相关性表明，在该人群中评估 RA 功能和 RV 舒张功能可能非常重要。

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查看原文本刊更多论文

Right Atrial Function and Right Ventricular Diastolic Function and Their Relation With Exercise Capacity in OSAS

Background

Right ventricular (RV) diastolic function and right atrial (RA) function are poorly characterized in patients with obstructive sleep apnea syndrome (OSAS), but may influence exercise capacity. We aimed to evaluate RA function and RV diastolic function in OSAS and study their relationship with exercise capacity.

Methods

Fifty-three patients with OSAS and thirty age- and gender-matched controls prospectively underwent echocardiography and cardiopulmonary exercise testing to investigate RV diastolic function, RA function, and exercise capacity.

Results

Altered RV diastolic function in patients with severe OSAS was indicated by the increased tricuspid valve E/e′ ratio (TV E/e′), isovolumic relaxation time (IVRT), and by the reduced RV TDI e′ velocity. The TV E/e′ correlated modestly with peak VO₂ (r = −0.334, p < 0.01). Patients with severe OSAS exhibited impaired RA total emptying fraction, RA passive emptying fraction, and RA reservoir strain (RARS), with RARS being associated with peak oxygen uptake (VO₂) (r = 0.451, p < 0.01 for reservoir function).

Conclusion

Altered RA function and RV diastolic function in patients with OSAS are associated with impaired exercise capacity. The correlation of RA function and RV diastolic function with exercise capacity suggests that it may be important to evaluate RA function and RV diastolic function in this population.

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来源期刊

Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques 医学-心血管系统

CiteScore

2.40

自引率

6.70%

发文量

211

审稿时长

3-6 weeks

期刊介绍： Echocardiography: A Journal of Cardiovascular Ultrasound and Allied Techniques is the official publication of the International Society of Cardiovascular Ultrasound. Widely recognized for its comprehensive peer-reviewed articles, case studies, original research, and reviews by international authors. Echocardiography keeps its readership of echocardiographers, ultrasound specialists, and cardiologists well informed of the latest developments in the field.