从模式到路径:衰老自我知觉的潜在阶级轨迹及其对多状态功能转变的因果影响

IF 3.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY
Lingjun Liu , Boshu Mao , Fei Ji
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引用次数: 0

摘要

目的探讨老年人衰老自我知觉的异质性发展轨迹及其对功能健康转变的因果影响。具体而言,我们旨在确定SPA发展的潜在类别,评估其对多状态功能转换的影响,并量化归因于负SPA的健康预期寿命损失。方法参考2008-2018年中国健康寿命纵向调查;n = 14,020),我们实施了潜在类别轨迹模型来识别SPA的发展模式。然后,我们应用多状态马尔可夫模型来检验SPA对功能状态(完全独立、需要援助和死亡)之间转换的影响,并建立了一个反事实框架来估计SPA导致的多状态预期寿命损失。结果分析显示两种不同的SPA轨迹:高水平组(57.75%)和低水平组(42.25%),均呈现下降趋势,但保持一致的水平差异。在调整人口统计学特征后,SPA阴性显著增加功能损害的风险(HR=1.31, 95% CI: 1.20-1.44),降低功能恢复的可能性(HR=0.61, 95% CI: 0.53-0.71)。在65岁时,SPA阴性与总预期寿命减少2.18年相关,健康预期寿命存在显著差异(10.93年对7.96年)。本研究揭示了老年SPA的两种不同轨迹,并论证了其对健康状态转变的因果影响。针对负面衰老认知的早期干预措施,特别是在65岁之前,可能有效延长健康预期寿命。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
From patterns to pathways: Latent class trajectories of self-perceptions of aging and their causal effects on multi-state functional transitions

Objectives

This study examines the heterogeneous developmental trajectories of self-perceptions of aging (SPA) and their causal effects on functional health transitions in older adults. Specifically, we aim to identify latent classes of SPA development, assess their impact on multi-state functional transitions, and quantify the loss in healthy life expectancy attributable to negative SPA.

Methods

Drawing from the Chinese Longitudinal Healthy Longevity Survey (2008–2018; n = 14,020), we implemented latent class trajectory modeling to identify SPA developmental patterns. We then applied multi-state Markov models to examine the effects of SPA on transitions among functional states (fully independent, assistance needed, and deceased), and established a counterfactual framework to estimate the loss in multi-state life expectancy attributable to SPA.

Results

Analysis revealed two distinct SPA trajectories: a high-level group (57.75 %) and a low-level group (42.25 %), both exhibiting declining trends while maintaining consistent level differences. After adjusting for demographic characteristics, negative SPA significantly increased the risk of functional impairment (HR=1.31, 95 % CI: 1.20–1.44) and diminished the probability of functional recovery (HR=0.61, 95 % CI: 0.53–0.71). At age 65, negative SPA was associated with a 2.18-year reduction in total life expectancy, with substantial disparities in healthy life expectancy (10.93 vs. 7.96 years).

Discussion

This study reveals two distinct trajectories of SPA in later life and demonstrates its causal effects on health state transitions. Early interventions targeting negative aging perceptions, particularly before age 65, may effectively extend healthy life expectancy.
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来源期刊
CiteScore
7.30
自引率
5.00%
发文量
198
审稿时长
16 days
期刊介绍: Archives of Gerontology and Geriatrics provides a medium for the publication of papers from the fields of experimental gerontology and clinical and social geriatrics. The principal aim of the journal is to facilitate the exchange of information between specialists in these three fields of gerontological research. Experimental papers dealing with the basic mechanisms of aging at molecular, cellular, tissue or organ levels will be published. Clinical papers will be accepted if they provide sufficiently new information or are of fundamental importance for the knowledge of human aging. Purely descriptive clinical papers will be accepted only if the results permit further interpretation. Papers dealing with anti-aging pharmacological preparations in humans are welcome. Papers on the social aspects of geriatrics will be accepted if they are of general interest regarding the epidemiology of aging and the efficiency and working methods of the social organizations for the health care of the elderly.
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