微生物简介:委内瑞拉链霉菌-一种研究丝状细菌形态和分化的模式物种。

IF 2.6 4区 生物学 Q3 MICROBIOLOGY
Max L Jordan, Susan Schlimpert
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引用次数: 0

摘要

链霉菌以其多细胞生活方式和生产生物活性分子(天然产物)而闻名,在医学,农业和工业中具有重要应用。对几种链霉菌的研究为了解它们的生物学和代谢提供了基础。然而,由于其复杂的生命周期,研究这些卓越细菌的形态发生和发育的时空过程在技术上具有挑战性。采用委内瑞拉链霉菌作为新的实验模式种,克服了这些局限性,为充分探索链霉菌发育的调控和细胞生物学打开了大门。委内瑞拉葡萄球菌的一个关键优势是它能够在液体培养中完成整个生命周期,促进了全基因组分析技术和先进细胞生物学方法的有效使用。这为链霉菌生长、分裂、发育转变和基因组组织的调控网络和分子机制提供了重要的新见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microbe Profile: Streptomyces venezuelae - a model species to study morphology and differentiation in filamentous bacteria.

Streptomyces bacteria are renowned for their multicellular lifestyle and production of bioactive molecules (natural products) with important applications in medicine, agriculture and industry. Studies of several Streptomyces species have provided a foundational understanding of their biology and metabolism. However, investigating the spatiotemporal processes governing the morphogenesis and development of these remarkable bacteria has been technically challenging due to their complex life cycle. The adoption of Streptomyces venezuelae as a new experimental model species has overcome these limitations and opened the door to fully explore the regulation and cell biology of Streptomyces development. A key advantage of S. venezuelae is its ability to complete its entire life cycle in liquid culture, facilitating the effective use of genome-wide analysis techniques and advanced cell biology approaches. This has provided significant new insights into the regulatory networks and molecular mechanisms underlying Streptomyces growth, division, developmental transitions and genome organization.

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来源期刊
Microbiology-Sgm
Microbiology-Sgm 生物-微生物学
CiteScore
4.60
自引率
7.10%
发文量
132
审稿时长
3.0 months
期刊介绍: We publish high-quality original research on bacteria, fungi, protists, archaea, algae, parasites and other microscopic life forms. Topics include but are not limited to: Antimicrobials and antimicrobial resistance Bacteriology and parasitology Biochemistry and biophysics Biofilms and biological systems Biotechnology and bioremediation Cell biology and signalling Chemical biology Cross-disciplinary work Ecology and environmental microbiology Food microbiology Genetics Host–microbe interactions Microbial methods and techniques Microscopy and imaging Omics, including genomics, proteomics and metabolomics Physiology and metabolism Systems biology and synthetic biology The microbiome.
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