[快速眼动睡眠行为障碍-不仅仅是简单的睡眠异常]。

Q4 Medicine
Carolin Schäfer, Anne-Kathrin Brill, Marie-Angela Wulf, Markus Schmidt, Claudio L Bassetti
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引用次数: 0

摘要

简介:快速眼动(REM)睡眠是睡眠的重要组成部分,主宰着下半晚的睡眠。快速眼动睡眠的生理性肌肉张力低下会导致做梦:快速眼动睡眠行为障碍(RBD)。在没有中枢神经系统疾病或诱发因素(如睡眠呼吸暂停、饮酒或抗抑郁药)的情况下,孤立性RBD (iRBD)可能存在。IRBD是α -突触核蛋白病的早期阶段,如帕金森病、路易体痴呆和多系统萎缩。病史和多导睡眠图是最重要的诊断工具。氯硝西泮和褪黑素是用来防止受伤的对症治疗。新技术能够长期监测iRBD的疾病进展,从而指导有针对性地使用未来的疾病修饰疗法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[REM-Sleep-Behavior Disorder - More Than a Simple Parasomnia].

Introduction: Rapid-Eye-Movement (REM) sleep is an essential part of sleep dominating the second half of the night. A disturbance of the phy-siological muscle hypotonia of REM sleep can lead to dream enactment: REM sleep behavior disorder (RBD). In the absence of a disease of the central nervous system or provoking factors such as sleep apnea, alcohol consumption or antidepressants, isolated RBD (iRBD) may be present. IRBD is an early stage of alpha-synucleinopathies such as Parkinson's disease, dementia with Lewy bodies and multisystem atrophy. Medical history and polysomnography are the most important diagnostic tools. Clonazepam and melatonin are symptomatic treatments used to prevent injury. New technologies enable long-term monitoring of disease progression in iRBD and thus guide the targeted use of future disease-modifying therapies.

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来源期刊
Praxis
Praxis Medicine-Medicine (all)
CiteScore
0.40
自引率
0.00%
发文量
146
审稿时长
12 weeks
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