内侧半月板挤压与老年人在跑步机行走时机械负荷后的急性软骨变形有关

IF 1.6 4区医学 Q3 ORTHOPEDICS

Knee Pub Date : 2025-03-13 DOI:10.1016/j.knee.2025.02.021

Shogo Okada , Masashi Taniguchi , Masahide Yagi , Yoshiki Motomura , Sayaka Okada , Kaede Nakazato , Yoshihiro Fukumoto , Kenta Iwane , Masashi Kobayashi , Kyoseki Kanemitsu , Noriaki Ichihashi

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引用次数: 0

摘要

本研究旨在探讨内侧半月板挤压（MME）引起的半月板功能恶化是否与机械载荷后股骨内侧软骨的急性变形有关，这种变形取决于软骨受到的接触力。方法：这是我们先前研究老年妇女机械负荷后急性软骨变形的二次分析。56名年龄≥50岁的女性参加了先前的研究，其中48名（年龄：70.3±7.6岁）参加了半月板评估，并被纳入本次分析。使用站立位置获得的b超图像评估MME。在跑步机步行15分钟后，根据软骨厚度的减少来评估急性软骨变形。机械累积负荷通过将膝关节内收力矩正值的时间积分乘以在跑步机上行走的步数来计算。采用配对t检验比较行走前后的软骨厚度。此外，我们还进行了多元线性回归分析，探讨MME是否与步行后急性软骨变形有关。结果在跑步机上行走后软骨发生明显变形（行走前：1.6±0.3 mm，行走后：1.5±0.3 mm）；0.001，效应量(r) = 0.760)。MME与步行后急性软骨变形量相关，与累积机械负荷或软骨状况无关（非标准化回归系数B = 0.013, 95%可信区间：0.001-0.025,P = 0.033，效应量(R2) = 0.144）。结论MME越大，机械负荷后急性软骨变形增加。

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Medial meniscus extrusion is associated with acute cartilage deformation after mechanical loading during treadmill walking in older adults

Background

This study aimed to investigate whether the worsening of meniscus function caused by medial meniscus extrusion (MME) was associated with acute cartilage deformation in the medial femur after mechanical loading, which changes depending on the contact force on the cartilage.

Methods

This was a secondary analysis of our previous study investigating acute cartilage deformation after mechanical loading in older women. Fifty-six women, aged ≥50 years, participated in the previous study, 48 of whom (age: 70.3 ± 7.6 years) participated in the meniscus assessment and were included in this analysis. MME was assessed using ultrasonographic B-mode images acquired in the standing position. Acute cartilage deformation was assessed based on the reduction in cartilage thickness after 15 min of treadmill walking. The mechanical cumulative loading was calculated by multiplying the time integrals of the positive values of the knee adduction moment, as assessed by motion analysis with the number of steps taken during treadmill walking. Paired t-tests were performed to compare cartilage thickness in pre- and post-walking. In addition, multiple linear regression analysis was performed to investigate whether MME was associated with acute cartilage deformation after walking.

Results

Significant cartilage deformation occurred after treadmill walking (pre-walking: 1.6 ± 0.3 mm, post-walking: 1.5 ± 0.3 mm, P < 0.001, effect size (r) = 0.760). MME was associated with the amount of acute cartilage deformation after walking, independent of cumulative mechanical loading or cartilage condition (unstandardized regression coefficient B = 0.013, 95% confidence interval: 0.001–0.025, P = 0.033, effect size (R²) = 0.144).

Conclusion

Greater MME is associated with increased acute cartilage deformation after mechanical loading.

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来源期刊

Knee 医学-外科

CiteScore

3.80

自引率

5.30%

发文量

171

审稿时长

6 months

期刊介绍： The Knee is an international journal publishing studies on the clinical treatment and fundamental biomechanical characteristics of this joint. The aim of the journal is to provide a vehicle relevant to surgeons, biomedical engineers, imaging specialists, materials scientists, rehabilitation personnel and all those with an interest in the knee. The topics covered include, but are not limited to: • Anatomy, physiology, morphology and biochemistry; • Biomechanical studies; • Advances in the development of prosthetic, orthotic and augmentation devices; • Imaging and diagnostic techniques; • Pathology; • Trauma; • Surgery; • Rehabilitation.