EZH1抑制产生成熟的ipsc衍生的CAR - T细胞，具有增强的抗肿瘤活性

IF 20.4 1区医学 Q1 CELL & TISSUE ENGINEERING

Cell stem cell Pub Date : 2025-03-14 DOI:10.1016/j.stem.2025.03.006

Ran Jing, Irene Scarfo, Mohamad Ali Najia, Edroaldo Lummertz da Rocha, Areum Han, Michael Sanborn, Trevor Bingham, Caroline Kubaczka, Deepak K. Jha, Marcelo Falchetti, Thorsten M. Schlaeger, Trista E. North, Marcela V. Maus, George Q. Daley

引用次数: 0

摘要

细胞干细胞29,1181-1196.e1-e6；2022年8月4日)

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity

(Cell Stem Cell 29, 1181–1196.e1–e6; August 4, 2022)

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来源期刊

Cell stem cell 生物-细胞生物学

CiteScore

37.10

自引率

2.50%

发文量

151

审稿时长

42 days

期刊介绍： Cell Stem Cell is a comprehensive journal covering the entire spectrum of stem cell biology. It encompasses various topics, including embryonic stem cells, pluripotency, germline stem cells, tissue-specific stem cells, differentiation, epigenetics, genomics, cancer stem cells, stem cell niches, disease models, nuclear transfer technology, bioengineering, drug discovery, in vivo imaging, therapeutic applications, regenerative medicine, clinical insights, research policies, ethical considerations, and technical innovations. The journal welcomes studies from any model system providing insights into stem cell biology, with a focus on human stem cells. It publishes research reports of significant importance, along with review and analysis articles covering diverse aspects of stem cell research.