D C S Onório, L B V Nunes, B M M B Nunes, S M S Ferreira, L A B Silva, G M França
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引用次数: 0
摘要
腺样囊性癌(ACC)是一种常见于大小唾液腺的肿瘤,具有很高的转移风险。因此,本研究的目的是进行分析,以更好地了解ACC的组织学分级系统及其对肿瘤预后的影响,包括总生存期、无病期和无转移期。这是一项基于PRISMA参数的系统综述,并进行了荟萃分析。检索由两名独立审查员进行,检索在PubMed、Web of Science、Scopus、Science Direct和谷歌Scholar数据库中进行。在纳入系统评价的12篇文章中,只有7篇符合进入荟萃分析的资格标准,具有实体模式的肿瘤与疾病死亡(DOD)之间存在统计学上显著的关联(p
Tumor classification of adenoid cystic carcinoma: systematic review and meta-analysis.
Adenoid Cystic Carcinoma - ACC is a common neoplasm in major and minor salivary glands with a high risk of metastasis. Thus, the objective of the present study was to perform an analysis to better understand the histological grading systems of the ACC and its influence on tumor prognosis in terms of overall survival, disease-free and metastasis-free. This is a systematic review, with meta-analysis, based on the PRISMA parameters. The search was carried out by two independent examiners, and searches were performed in the PubMed, Web of Science, Scopus, Science Direct, and Google Scholar databases. Of the 12 articles included in the systematic review, only 7 met the eligibility criteria for entry into the meta-analysis, with a statistically significant association between tumors with a solid pattern and death from the disease (DOD) (p <0.001; 95% CI 2.84 [1.94-4.15]; I 2 61%). Regarding the evaluation of the quality of studies by the Quality in Prognostic Studies (QUIPS), six studies were of high quality, five articles received moderate quality, and one article received low quality. It was concluded that the presence of any solid component contributes to a worse prognosis and lower specific survival of the disease over the 10 years.
期刊介绍:
The BJB – Brazilian Journal of Biology® is a scientific journal devoted to publishing original articles in all fields of the Biological Sciences, i.e., General Biology, Cell Biology, Evolution, Biological Oceanography, Taxonomy, Geographic Distribution, Limnology, Aquatic Biology, Botany, Zoology, Genetics, and Ecology. Priority is given to papers presenting results of researches in the Neotropical region. Material published includes research papers, review papers (upon approval of the Editorial Board), notes, book reviews, and comments.