Silvia Cañizares, Laura Nuño, Pablo Barrio, Mireia Forner-Puntonet, Carolina Gavotti, Miquel Monràs, Patricia Gavín, Ricard Navinés, Lilliam Flores, Maite Barrios, Alba Andreu, Judit Molero, Amanda Jimenez, Josep Vidal, Anna Lligoña
{"title":"减肥手术候选人的酒精和其他物质筛选:自我报告和毒理学测试的效用,包括乙基糖甙","authors":"Silvia Cañizares, Laura Nuño, Pablo Barrio, Mireia Forner-Puntonet, Carolina Gavotti, Miquel Monràs, Patricia Gavín, Ricard Navinés, Lilliam Flores, Maite Barrios, Alba Andreu, Judit Molero, Amanda Jimenez, Josep Vidal, Anna Lligoña","doi":"10.1007/s11695-025-07774-z","DOIUrl":null,"url":null,"abstract":"<p><p>Following bariatric surgery (BS) patients have an increased risk of alcohol misuse.</p><p><strong>Purpose: </strong>This 1-year cross-sectional study in potential BS candidates had several objectives: (a) assess the prevalence of risky drinking, alcohol use disorder (AUD), and other substance use/disorder; (b) compare the prevalence of these behaviors to that of the general Spanish population; (c) determine the proportion of patients with positive results in toxicology tests; and (d) study the predictive factors of risky drinking.</p><p><strong>Setting: </strong>tertiary university hospital.</p><p><strong>Materials and methods: </strong>Alcohol and other substance use were evaluated with the AUDIT-C and ASSIST questionnaires. Urine tests analyzed several markers (ethyl-glucoronide [EtG] ≥ 500 ng/ml, amphetamine, benzodiazepine, cannabinoid, cocaine, and opioid). The Mini-International-Neuropsychiatric-Interview (5.0.0) was employed to assess psychiatric diagnoses.</p><p><strong>Results: </strong>Among 308 candidates for BS, 196 were accepted to participate (69% women; mean age 46.7 ± 10.9 years; mean body mass index 45.6 ± 5.9). AUDIT-C and ASSIST identified 7% and 5% of risky drinkers, respectively. Men were more frequently risky drinkers compared to women (18% vs. 2%) and compared to the general population (18% vs. 8%). Six percent of individuals had AUD, being men the most affected, and 2% met criteria for other substance disorder. Fifteen percent of the sample presented risky tobacco use. Cannabis was self-reported only by males (3%). EtG ≥ 500 ng/ml was present in 15% of the sample, being a risk factor for risky drinking together with the male sex.</p><p><strong>Conclusion: </strong>Identification of candidates at risk for risky drinking can help to prevent any alcohol misuse after BS. The combination of subjective and objective measures improves the validity of the assessment of substance use.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":" ","pages":"1242-1250"},"PeriodicalIF":2.9000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Alcohol and Other Substance Screening in Bariatric Surgery Candidates: Utility of Self-Report and Toxicology Tests, Including Ethyl-Glucoronide.\",\"authors\":\"Silvia Cañizares, Laura Nuño, Pablo Barrio, Mireia Forner-Puntonet, Carolina Gavotti, Miquel Monràs, Patricia Gavín, Ricard Navinés, Lilliam Flores, Maite Barrios, Alba Andreu, Judit Molero, Amanda Jimenez, Josep Vidal, Anna Lligoña\",\"doi\":\"10.1007/s11695-025-07774-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Following bariatric surgery (BS) patients have an increased risk of alcohol misuse.</p><p><strong>Purpose: </strong>This 1-year cross-sectional study in potential BS candidates had several objectives: (a) assess the prevalence of risky drinking, alcohol use disorder (AUD), and other substance use/disorder; (b) compare the prevalence of these behaviors to that of the general Spanish population; (c) determine the proportion of patients with positive results in toxicology tests; and (d) study the predictive factors of risky drinking.</p><p><strong>Setting: </strong>tertiary university hospital.</p><p><strong>Materials and methods: </strong>Alcohol and other substance use were evaluated with the AUDIT-C and ASSIST questionnaires. Urine tests analyzed several markers (ethyl-glucoronide [EtG] ≥ 500 ng/ml, amphetamine, benzodiazepine, cannabinoid, cocaine, and opioid). The Mini-International-Neuropsychiatric-Interview (5.0.0) was employed to assess psychiatric diagnoses.</p><p><strong>Results: </strong>Among 308 candidates for BS, 196 were accepted to participate (69% women; mean age 46.7 ± 10.9 years; mean body mass index 45.6 ± 5.9). AUDIT-C and ASSIST identified 7% and 5% of risky drinkers, respectively. Men were more frequently risky drinkers compared to women (18% vs. 2%) and compared to the general population (18% vs. 8%). Six percent of individuals had AUD, being men the most affected, and 2% met criteria for other substance disorder. Fifteen percent of the sample presented risky tobacco use. Cannabis was self-reported only by males (3%). EtG ≥ 500 ng/ml was present in 15% of the sample, being a risk factor for risky drinking together with the male sex.</p><p><strong>Conclusion: </strong>Identification of candidates at risk for risky drinking can help to prevent any alcohol misuse after BS. 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引用次数: 0
摘要
减肥手术(BS)后,患者酒精滥用的风险增加。目的:这项针对潜在BS候选人的为期1年的横断面研究有几个目标:(a)评估危险饮酒、酒精使用障碍(AUD)和其他物质使用/障碍的患病率;(b)将这些行为的普遍程度与西班牙一般人口的普遍程度进行比较;(c)确定毒理学试验结果呈阳性的患者比例;(d)研究危险饮酒的预测因素。单位:第三大学附属医院。材料和方法:采用AUDIT-C和ASSIST问卷对酒精和其他物质使用情况进行评估。尿检分析了几种标记物(乙基-葡萄糖酸盐[EtG]≥500 ng/ml,安非他明,苯二氮卓类,大麻素,可卡因和阿片类药物)。采用mini - international - neuropsychiatry - interview(5.0.0)评估精神诊断。结果:在308名BS候选人中,196人被接受参加(69%为女性;平均年龄46.7±10.9岁;平均体重指数(45.6±5.9)。AUDIT-C和ASSIST分别确定了7%和5%的高危饮酒者。与女性相比(18%对2%),与一般人群相比(18%对8%),男性更频繁地冒险饮酒者。6%的人患有澳元,男性受影响最大,2%的人符合其他物质障碍的标准。15%的样本存在危险的烟草使用。只有男性自我报告吸食大麻(3%)。15%的样本中存在EtG≥500 ng/ml,与男性一起成为危险饮酒的危险因素。结论:识别有饮酒风险的候选人有助于预防BS后的任何酒精滥用。主客观措施相结合,提高了物质使用评估的效度。
Alcohol and Other Substance Screening in Bariatric Surgery Candidates: Utility of Self-Report and Toxicology Tests, Including Ethyl-Glucoronide.
Following bariatric surgery (BS) patients have an increased risk of alcohol misuse.
Purpose: This 1-year cross-sectional study in potential BS candidates had several objectives: (a) assess the prevalence of risky drinking, alcohol use disorder (AUD), and other substance use/disorder; (b) compare the prevalence of these behaviors to that of the general Spanish population; (c) determine the proportion of patients with positive results in toxicology tests; and (d) study the predictive factors of risky drinking.
Setting: tertiary university hospital.
Materials and methods: Alcohol and other substance use were evaluated with the AUDIT-C and ASSIST questionnaires. Urine tests analyzed several markers (ethyl-glucoronide [EtG] ≥ 500 ng/ml, amphetamine, benzodiazepine, cannabinoid, cocaine, and opioid). The Mini-International-Neuropsychiatric-Interview (5.0.0) was employed to assess psychiatric diagnoses.
Results: Among 308 candidates for BS, 196 were accepted to participate (69% women; mean age 46.7 ± 10.9 years; mean body mass index 45.6 ± 5.9). AUDIT-C and ASSIST identified 7% and 5% of risky drinkers, respectively. Men were more frequently risky drinkers compared to women (18% vs. 2%) and compared to the general population (18% vs. 8%). Six percent of individuals had AUD, being men the most affected, and 2% met criteria for other substance disorder. Fifteen percent of the sample presented risky tobacco use. Cannabis was self-reported only by males (3%). EtG ≥ 500 ng/ml was present in 15% of the sample, being a risk factor for risky drinking together with the male sex.
Conclusion: Identification of candidates at risk for risky drinking can help to prevent any alcohol misuse after BS. The combination of subjective and objective measures improves the validity of the assessment of substance use.
期刊介绍:
Obesity Surgery is the official journal of the International Federation for the Surgery of Obesity and metabolic disorders (IFSO). A journal for bariatric/metabolic surgeons, Obesity Surgery provides an international, interdisciplinary forum for communicating the latest research, surgical and laparoscopic techniques, for treatment of massive obesity and metabolic disorders. Topics covered include original research, clinical reports, current status, guidelines, historical notes, invited commentaries, letters to the editor, medicolegal issues, meeting abstracts, modern surgery/technical innovations, new concepts, reviews, scholarly presentations and opinions.
Obesity Surgery benefits surgeons performing obesity/metabolic surgery, general surgeons and surgical residents, endoscopists, anesthetists, support staff, nurses, dietitians, psychiatrists, psychologists, plastic surgeons, internists including endocrinologists and diabetologists, nutritional scientists, and those dealing with eating disorders.