裂脑患者:临床与实验的对比。

Q2 Medicine
Michael B Miller, Lukas J Volz, Jessica M Simonson, Michael S Gazzaniga
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引用次数: 0

摘要

80多年来,对劈裂脑手术行为结果的临床观点表明,尽管有一些最初和短暂的断开效应,但它“可能对患者没有任何不良影响”。然而,过去60年的实验研究却显示出截然相反的结果。使用侧化测试程序,裂脑患者表现出严重的断开连接效应,这种影响可能持续一生。这项实验工作改变了我们对半球特化和大脑不对称的理解。它描绘了一幅病人有两个不同的神经系统独立处理和运作的画面,然而,一个看似统一的意识体验。本章追踪了这两种不同的观点是如何共存这么长时间的,并从临床和社会的角度解释了为什么这些患者看起来很正常。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Split-brain patients: A clinical vs experimental perspective.

For more than 80 years, the clinical perspective on the behavioral outcome of split-brain surgery suggested that it "may be carried out without any untoward effect on the patient," despite some initial and transient disconnection effects. The last 60 years of experimental studies, however, have shown quite the opposite. Using lateralized testing procedures, split-brain patients have demonstrated profound disconnection effects that can last a lifetime. This experimental work has transformed our understanding of hemispheric specializations and cerebral asymmetries. It paints a picture of patients with two distinct neural systems processing and operating independently with, nevertheless, a seemingly unified conscious experience. This chapter tracks how these two divergent perspectives have coexisted for so long and offers some explanations for why these patients appear normal from a clinical and social perspective.

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来源期刊
Handbook of clinical neurology
Handbook of clinical neurology Medicine-Neurology (clinical)
CiteScore
4.10
自引率
0.00%
发文量
302
期刊介绍: The Handbook of Clinical Neurology (HCN) was originally conceived and edited by Pierre Vinken and George Bruyn as a prestigious, multivolume reference work that would cover all the disorders encountered by clinicians and researchers engaged in neurology and allied fields. The first series of the Handbook (Volumes 1-44) was published between 1968 and 1982 and was followed by a second series (Volumes 45-78), guided by the same editors, which concluded in 2002. By that time, the Handbook had come to represent one of the largest scientific works ever published. In 2002, Professors Michael J. Aminoff, François Boller, and Dick F. Swaab took on the responsibility of supervising the third (current) series, the first volumes of which published in 2003. They have designed this series to encompass both clinical neurology and also the basic and clinical neurosciences that are its underpinning. Given the enormity and complexity of the accumulating literature, it is almost impossible to keep abreast of developments in the field, thus providing the raison d''être for the series. The series will thus appeal to clinicians and investigators alike, providing to each an added dimension. Now, more than 140 volumes after it began, the Handbook of Clinical Neurology series has an unparalleled reputation for providing the latest information on fundamental research on the operation of the nervous system in health and disease, comprehensive clinical information on neurological and related disorders, and up-to-date treatment protocols.
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