从食用菌羊肚菌中分离的一种β内啡肽病毒的鉴定

IF 2.5 4区医学 Q3 VIROLOGY

Archives of Virology Pub Date : 2025-03-14 DOI:10.1007/s00705-025-06264-y

Ruiling Lyu, Junlin Chen, Qing Tang, Du Hai, Tun Wu, Huagang Xiao, Jiatao Xie, Yang Xiao

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引用次数: 0

摘要

从六口羊肚菌ZY-1株中分离到一株阳性单链RNA分枝病毒，命名为“六口羊肚菌内啡肽病毒1”（MsEV1）。发现MsEV1的完整基因组长度为16,589个核苷酸（nt），包含一个大的开放阅读框（ORF），在5477个氨基酸的多蛋白中编码病毒蛋白PRK00409、转甲基化酶、DEXDc、解旋酶和RdRP。基于RdRP核苷酸序列的系统发育分析表明，该内啡肽病毒属于内啡肽科Betaendornavirus属。

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Characterization of a betaendornavirus isolated from the edible fungus Morchella sextelata

A positive-sense single-stranded RNA mycovirus was isolated from Morchella sextelata strain ZY-1 and designated as “Morchella sextelata endornavirus 1” (MsEV1). The complete genome of MsEV1 was found to be 16,589 nucleotides (nt) in length and to contain a single large open reading frame (ORF) encoding the viral proteins PRK00409, transmethylase, DEXDc, helicase, and RdRP in a polyprotein of 5,477 amino acids. Phylogenetic analysis based on RdRP nucleotide sequences revealed that this endornavirus is a member of the genus Betaendornavirus in the family Endornaviridae.

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来源期刊

Archives of Virology 医学-病毒学

CiteScore

5.10

自引率

7.40%

发文量

324

审稿时长

4.5 months

期刊介绍： Archives of Virology publishes original contributions from all branches of research on viruses, virus-like agents, and virus infections of humans, animals, plants, insects, and bacteria. Coverage spans a broad spectrum of topics, from descriptions of newly discovered viruses, to studies of virus structure, composition, and genetics, to studies of virus interactions with host cells, organisms and populations. Studies employ molecular biologic, molecular genetics, and current immunologic and epidemiologic approaches. Contents include studies on the molecular pathogenesis, pathophysiology, and genetics of virus infections in individual hosts, and studies on the molecular epidemiology of virus infections in populations. Also included are studies involving applied research such as diagnostic technology development, monoclonal antibody panel development, vaccine development, and antiviral drug development.Archives of Virology wishes to publish obituaries of recently deceased well-known virologists and leading figures in virology.