Rabdomiólisis asociada a fenoverina: reporte de caso

Rhabdomyolysis is a syndrome characterized by muscle destruction and the release of intracellular contents into the plasma, this being one of the main potential causes of nephrotoxicity. Being a syndrome, its etiology is diverse; however, little has been described about rhabdomyolysis secondary to the consumption of HMG-CoA reductase inhibitor drugs such as Phenoverine.

The case of a 54-year-old female patient with no significant history is described, with a clinical picture characterized by asthenia, adynamia, muscle pain, arthralgia, and serum creatine kinase (CPK) of 53,032 IU/L, after the consumption of Phenoverine, complying with diagnostic criteria for rhabdomyolysis secondary to drug use. After the initial evaluation, conservative management was established, based on nephroprotective measures, presenting satisfactory improvement, with resolution of rhabdomyolysis and acute kidney injury.

The objective of this article is to report the case of rhabdomyolysis secondary to the use of this frequently used antispasmodic agent, and of which this complication is underestimated, which can become so serious and leave permanent kidney damage as a consequence.