PeiPei Zhang , XinYu Zhang , XueFei Li , YuXuan Wang , Hera Soha , Ahmed Elsheikh , QinXiang Zheng , Fan Lu , RuZhi Deng , JunJie Wang
{"title":"不同后视区直径角膜塑形术中角膜生物力学响应分析:比较有限元研究。","authors":"PeiPei Zhang , XinYu Zhang , XueFei Li , YuXuan Wang , Hera Soha , Ahmed Elsheikh , QinXiang Zheng , Fan Lu , RuZhi Deng , JunJie Wang","doi":"10.1016/j.clae.2025.102401","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><div>To investigate the impact of orthokeratology (<em>ortho</em>-k) lenses with different back optic zone diameter (BOZD) on the biomechanical response of the cornea, focusing on contact pressure, displacement, and stress distribution.</div></div><div><h3>Method</h3><div>Finite element models were developed to simulate varying corneal curvatures (39.0D, 42.0D, 45.0D) and <em>ortho</em>-k lenses designed to target myopia reductions of −2.0D, −4.0D, and −6.0D, with BOZD values of 5.0 mm and 6.0 mm. Key parameters—contact pressure, displacement, mechanical treatment zone (MTZ) diameter and von Mises stress—were calculated and compared across the models.</div></div><div><h3>Result</h3><div>The BOZD = 5 mm group demonstrated higher central contact pressure and greater central corneal displacement compared to the BOZD = 6 mm group. Additionally, the BOZD = 5 mm group exhibited a smaller central contact range, corneal reshaping range, and MTZ diameter than the BOZD = 6 mm group. The maximum stress decreased and shifted locations from the center to the periphery after lens application in both groups, with a more significant decrease observed in the 6 mm group.</div></div><div><h3>Conclusion</h3><div>BOZD plays a crucial role in corneal biomechanical responses during <em>ortho</em>-k treatment. Smaller BOZD lenses result in a more concentrated contact area, leading to a smaller corneal reshaping area and MTZ diameter without significantly increasing the maximum stress in the cornea.</div></div>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":"48 4","pages":"Article 102401"},"PeriodicalIF":3.7000,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Analyzing corneal biomechanical response in orthokeratology with differing back optic zone diameter: A comparative finite element study\",\"authors\":\"PeiPei Zhang , XinYu Zhang , XueFei Li , YuXuan Wang , Hera Soha , Ahmed Elsheikh , QinXiang Zheng , Fan Lu , RuZhi Deng , JunJie Wang\",\"doi\":\"10.1016/j.clae.2025.102401\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Purpose</h3><div>To investigate the impact of orthokeratology (<em>ortho</em>-k) lenses with different back optic zone diameter (BOZD) on the biomechanical response of the cornea, focusing on contact pressure, displacement, and stress distribution.</div></div><div><h3>Method</h3><div>Finite element models were developed to simulate varying corneal curvatures (39.0D, 42.0D, 45.0D) and <em>ortho</em>-k lenses designed to target myopia reductions of −2.0D, −4.0D, and −6.0D, with BOZD values of 5.0 mm and 6.0 mm. Key parameters—contact pressure, displacement, mechanical treatment zone (MTZ) diameter and von Mises stress—were calculated and compared across the models.</div></div><div><h3>Result</h3><div>The BOZD = 5 mm group demonstrated higher central contact pressure and greater central corneal displacement compared to the BOZD = 6 mm group. Additionally, the BOZD = 5 mm group exhibited a smaller central contact range, corneal reshaping range, and MTZ diameter than the BOZD = 6 mm group. The maximum stress decreased and shifted locations from the center to the periphery after lens application in both groups, with a more significant decrease observed in the 6 mm group.</div></div><div><h3>Conclusion</h3><div>BOZD plays a crucial role in corneal biomechanical responses during <em>ortho</em>-k treatment. Smaller BOZD lenses result in a more concentrated contact area, leading to a smaller corneal reshaping area and MTZ diameter without significantly increasing the maximum stress in the cornea.</div></div>\",\"PeriodicalId\":49087,\"journal\":{\"name\":\"Contact Lens & Anterior Eye\",\"volume\":\"48 4\",\"pages\":\"Article 102401\"},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2025-03-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Contact Lens & Anterior Eye\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1367048425000359\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Contact Lens & Anterior Eye","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1367048425000359","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Analyzing corneal biomechanical response in orthokeratology with differing back optic zone diameter: A comparative finite element study
Purpose
To investigate the impact of orthokeratology (ortho-k) lenses with different back optic zone diameter (BOZD) on the biomechanical response of the cornea, focusing on contact pressure, displacement, and stress distribution.
Method
Finite element models were developed to simulate varying corneal curvatures (39.0D, 42.0D, 45.0D) and ortho-k lenses designed to target myopia reductions of −2.0D, −4.0D, and −6.0D, with BOZD values of 5.0 mm and 6.0 mm. Key parameters—contact pressure, displacement, mechanical treatment zone (MTZ) diameter and von Mises stress—were calculated and compared across the models.
Result
The BOZD = 5 mm group demonstrated higher central contact pressure and greater central corneal displacement compared to the BOZD = 6 mm group. Additionally, the BOZD = 5 mm group exhibited a smaller central contact range, corneal reshaping range, and MTZ diameter than the BOZD = 6 mm group. The maximum stress decreased and shifted locations from the center to the periphery after lens application in both groups, with a more significant decrease observed in the 6 mm group.
Conclusion
BOZD plays a crucial role in corneal biomechanical responses during ortho-k treatment. Smaller BOZD lenses result in a more concentrated contact area, leading to a smaller corneal reshaping area and MTZ diameter without significantly increasing the maximum stress in the cornea.
期刊介绍:
Contact Lens & Anterior Eye is a research-based journal covering all aspects of contact lens theory and practice, including original articles on invention and innovations, as well as the regular features of: Case Reports; Literary Reviews; Editorials; Instrumentation and Techniques and Dates of Professional Meetings.