IF 2.6 4区 医学 Q2 OPHTHALMOLOGY
Agnieszka Leszyńska, Dominika Kozłowska, Julia Bałoniak, Julia Linke, Emilia Bachoń, Michalina Doligalska, Aleksandra Stremel, Wiktoria Wesołowska
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引用次数: 0

摘要

皮肤疾病常常伴有眼部症状。在这篇综述中,我们旨在确定某些皮肤病最常见的眼部表现,特别是银屑病、特应性皮炎、酒渣鼻和丘疹性荨麻疹。我们强调了与这些疾病相关的主要眼科疾病,以提高在临床实践中可能会遇到这些皮肤病患者的眼科医生的认识。通过分析原始研究,最常见的眼部表现包括各种类型的炎症,如结膜炎和睑缘炎。此外,角膜炎、葡萄膜炎和睑板腺功能障碍等更严重的情况也经常出现。丘疹性荨麻疹和酒渣鼻的眼部症状可能先于皮肤症状出现。干眼症常见于各种皮肤病。钙调素抑制剂(用于特应性皮炎和银屑病)等治疗方法对皮肤病和眼部症状都有疗效。在特应性皮炎中,使用杜必鲁单抗与结膜炎发病率的增加有关,这就需要皮肤科医生和眼科医生合作,将药物副作用与疾病表现区分开来。银屑病治疗,包括光疗和生物制剂(如 secukinumab 和 ustekinumab),需要仔细监测对眼睛的潜在影响,因为它们的安全性仍在评估中。对于眼部红斑痤疮,环孢素在控制烧灼感和角膜受累等症状方面的疗效优于强力霉素。本综述强调了认识到皮肤病与眼部健康之间相互作用的重要性。早期诊断、跨学科合作和有针对性的治疗对于有效控制这些复杂的病情至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ocular Manifestations in Selected Dermatological Disorders: A Narrative Review.

Skin disorders are often associated with ocular symptoms. In this review, we aim to identify the most common ocular manifestations observed in selected dermatological diseases, specifically psoriasis, atopic dermatitis, rosacea, and pemphigus. We highlight key ophthalmological conditions linked to these diseases to raise awareness among ophthalmologists who may encounter patients with these dermatological conditions in their clinical practice. Analyzing the original studies, the most common ocular manifestations include various types of inflammation, such as conjunctivitis and blepharitis. Additionally, more severe conditions, such as keratitis, uveitis, and meibomian gland dysfunction, are frequently observed. Ocular symptoms in pemphigus vulgaris and rosacea can precede dermatological signs. Dry eye disease is commonly seen across various dermatological conditions. Treatments like calcineurin inhibitors (used for atopic dermatitis and psoriasis) have shown efficacy for both dermatological and ocular symptoms. In atopic dermatitis, the use of dupilumab has been linked to increased rates of conjunctivitis, necessitating collaboration between dermatologists and ophthalmologists to distinguish drug side effects from disease manifestations. Psoriasis treatments, including phototherapy and biologics like secukinumab and ustekinumab, require careful monitoring for potential ocular effects, as their safety profiles are still being evaluated. For ocular rosacea, cyclosporine has demonstrated superior efficacy over doxycycline in managing symptoms such as burning and corneal involvement. This review underscores the importance of recognizing the interplay between dermatological and ocular health. Early diagnosis, interdisciplinary collaboration, and tailored treatments are essential for managing these complex conditions effectively.

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来源期刊
CiteScore
6.20
自引率
15.20%
发文量
285
审稿时长
6-12 weeks
期刊介绍: Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.
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