镜检辅助腔内小梁切开术后长期眼压变化模式:两年的结果。

IF 1.8 4区 医学 Q2 OPHTHALMOLOGY
Journal of Glaucoma Pub Date : 2025-08-01 Epub Date: 2025-03-13 DOI:10.1097/IJG.0000000000002565
Bruno M Faria, Diego T Dias, Mariana A O Reis, Fabio B Daga, Ana L B Scoralick, Leopoldo Magacho, Pedro H E Ribeiro Junior, Fabio N Kanadani, Vital P Costa, Tiago S Prata
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引用次数: 0

摘要

临床控制不佳的开角型青光眼患者,在24个月的随访中,接受单独的gonioscopy辅助腔内小梁切开术或联合超声乳化术,不仅获得了较低的平均IOP,而且显示出稳定的IOP模式。目的:探讨经腔镜辅助的小梁切开术(GATT)对长期眼压(IOP)变化的影响。患者和方法:一项单中心回顾性研究,纳入了169例因临床不可控开角型青光眼而接受单独GATT或联合超声乳化术(PHACOGATT)的患者,随访至少12个月。观察长期平均IOP、长期IOP峰值、长期IOP波动、变异系数、平均IOP阳性变异、持续临床显著性IOP阳性变异和IOP≥15 mmHg随访次数。结果:纳入169例患者169只眼(GATT组=101例;PHACOGATT组=68例)。PHACOGATT组的平均长期IOP(12.0±1.8比11.2±2.0 mmHg)、平均长期IOP峰值(12.9±2.6比11.8±3.5 mmHg)和平均变异系数(0.07±0.08比0.05±0.09)较低,而GATT组的平均IOP波动(1.0±3.7比1.2±1.8 mmHg)较低。此外,总体平均阳性IOP变化为0.79±1.64 mmHg。最后,只有6.5%的患者出现持续的临床显著的IOP阳性变化,5.9%的随访患者IOP≥15 mmHg。结论:经GATT或PHACOGATT治疗的开角型青光眼患者平均眼压较低,眼压模式稳定。我们的研究结果提供了额外的证据,支持GATT和PHACOGATT作为治疗需要低和稳定IOPs的医学上不受控制的青光眼患者的可行选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pattern of Long-Term Intraocular Pressure Variation Following Gonioscopy-Assisted Transluminal Trabeculotomy: Two-Year Outcomes.

Prcis: Patients with clinically uncontrolled open angle glaucoma submitted to isolated gonioscopy-assisted transluminal trabeculotomy or combined with phacoemulsification not only achieved low mean IOPs, but also demonstrated stable IOP patterns during a 24-month follow-up.

Purpose: To assess the impact of gonioscopy-assisted transluminal trabeculotomy (GATT) on long-term intraocular pressure (IOP) variation.

Patients and methods: An unicentric retrospective study including 169 consecutive patients who had undergone standalone GATT or combined with phacoemulsification (PHACOGATT) due to clinically uncontrolled open angle glaucoma, with at least 12 months of follow-up was conducted. Long-term mean IOP, long-term IOP peak, long-term IOP fluctuation, coefficient of variation, mean-positive IOP variation, sustained clinically significant positive IOP variation, and number of follow-up visits with IOP ≥15 mm Hg were investigated.

Results: One hundred sixty-nine eyes from 169 patients were included (GATT group=101 patients; PHACOGATT group=68 patients). Mean long term IOP (12.0±1.8 vs. 11.2±2.0 mm Hg), mean long-term IOP peak (12.9±2.6 vs. 11.8±3.5 mm Hg), and mean coefficient of variation (0.07±0.08 vs. 0.05±0.09) were lower in the PHACOGATT group, while mean IOP fluctuation (1.0±3.7 vs. 1.2±1.8 mm Hg) was lower in the GATT group. In addition, the overall mean-positive IOP variation was 0.79±1.64 mm Hg. Finally, only 6.5% of the patients presented sustained clinically significant positive IOP variation and IOP was ≥15 mm Hg in 5.9% of the follow-up visits.

Conclusions: Patients with clinically uncontrolled open angle glaucoma submitted to GATT or PHACOGATT achieved low mean IOPs and demonstrated stable IOP patterns. Our results provide additional evidence supporting GATT and PHACOGATT as viable options for the treatment of medically uncontrolled glaucoma patients requiring low and stable IOPs.

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来源期刊
Journal of Glaucoma
Journal of Glaucoma 医学-眼科学
CiteScore
4.20
自引率
10.00%
发文量
330
审稿时长
4-8 weeks
期刊介绍: The Journal of Glaucoma is a peer reviewed journal addressing the spectrum of issues affecting definition, diagnosis, and management of glaucoma and providing a forum for lively and stimulating discussion of clinical, scientific, and socioeconomic factors affecting care of glaucoma patients.
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